Effectiveness of Facet Joint Infiltration in Low Back Pain

NCT ID: NCT01447160

Last Updated: 2011-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2012-04-30

Brief Summary

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The purpose of this study is to evaluate the effectiveness of facet joint infiltration with corticosteroids in the treatment of low back pain due to facet joint osteoarthritis.

Detailed Description

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Sixty subjects with diagnostic of facet joint syndrome will be enrolled in the study.

They were randomized into experimental and control groups. The experimental group will be submitted to intra-articular infiltration of six facet joints. The control group will be submitted to intramuscular injection of six lumbar paravertebral points. After the randomization, all subjects will be assessed by an investigator blinded to the groups. The assessment will be taken just before the interventions (T0) and them 7 , 30 , 90 and 180 days after the interventions. The following assessment instruments will be used: pain visual analogical scale (VAS) (0-10cm), pain visual analogical scale during extension of the spine (VAS E) (0-10cm), Likert scale for improving (0-5), percentage scale of subjective improving perception(0-100%), Rolland-Morris questionnaire (0-24), short health survey questionnaire (SF36), accountability of medications taken for back pain: analgesics and non-steroidal antiinflammatories (NSAIDs).

Conditions

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Low Back Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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facet joint infiltration

The experimental group will be submitted to intra-articular infiltration of six facet joints (L3/L4;L4/L5;L5/S1 bilaterally) with triamcinolone hexacetonide

Group Type EXPERIMENTAL

Cortisone

Intervention Type DRUG

intraarticular infiltration with 1ml of triamcinolone hexacetonide versus intramuscular injection with 1 ml of triamcinolone acetonide

intramuscular injection

The control group which were submitted to triamcinolone acetonide intramuscular injection of six lumbar paravertebral points

Group Type ACTIVE_COMPARATOR

Cortisone

Intervention Type DRUG

intraarticular infiltration with 1ml of triamcinolone hexacetonide versus intramuscular injection with 1 ml of triamcinolone acetonide

Interventions

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Cortisone

intraarticular infiltration with 1ml of triamcinolone hexacetonide versus intramuscular injection with 1 ml of triamcinolone acetonide

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* low back pain up to 3 months
* pain on back extension
* radiologic findings of facet joint osteoarthritis

Exclusion Criteria

* other causes of back pain
* fibromyalgia
* diabetes, arterial hypertension or glaucoma not well controlled
* patients with contrast allergy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federal University of São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Federal University of São Paulo

Principal Investigators

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Luiza Ribeiro, doctor

Role: PRINCIPAL_INVESTIGATOR

Sao Paulo Federal University

Locations

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Sao Paulo federal University

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

Central Contacts

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luiza ribeiro, doctor

Role: CONTACT

55-11 92678027

Other Identifiers

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FUSao Paulo

Identifier Type: -

Identifier Source: org_study_id