Effect of an Acute Bout of Exercise on Smoking Topography

NCT ID: NCT01431365

Last Updated: 2014-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2014-12-31

Brief Summary

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Smokers will complete questionnaires and smoking behaviour will be examined. After abstaining from smoking for approximately 18 hours, they will be randomized to a moderate intensity exercise group or passive sitting group. Smoking behaviour (time to first puff) will be assessed following treatment.

Detailed Description

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Lung cancer is the leading cause of cancer death in Canadians (Canadian Cancer Society, in which cigarette smoking is responsible for 85% of these cases. Smoking topography, a key facet of smoking behaviour, can be subjectively or objectively measured by quantifying puff volume, maximum puff velocity, interpuff interval, puff duration, number of puffs per cigarette, and the time to smoke a single cigarette. Smoking topography can estimate exposure to carcinogenic toxins present in cigarette smoking (Djordjevic, Hoffman, \& Hoffman, 1997). Evidence exists to support that exercise modifies smoking topography (Katomeri \& Taylor 2006; Mikhail, 1983; Reeser, 1983; Zacny \& Stitzer, 1985).

Recently, Faulkner and colleagues (2011; N = 18) were the first to implement a handheld smoking topography device (CReSS Pocket) to measure smoking behaviour in the context of an acute bout of exercise after a temporary period of abstinence. They found that brisk walking influences an individual's smoking topography. In specific, participants assigned to the exercise condition smoked less per puff and took shorter puff durations, compared to the passive sitting condition. Overall, smoking topographical studies require further investigation due to methodological flaws in order to allow for the objective collection of smoking behaviour data and improved external validity in a sufficiently powered study. Furthermore, the role of cravings, withdrawal and affect as potential mediators of topographical changes due to exercise is a novel area of research.

Conditions

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Cancer

Keywords

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exercise topography cravings smoking behaviour

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Moderate Exercise Group

The moderate exercise condition will involve participants walking briskly (equivalent to moderate intensity) on a treadmill for 10 minutes. Moderate intensity exercise will be defined as 40-68% of the resting heart rate reserve. Heart rate (HR) will be monitored in participants using a Polar RS100 Heart Rate monitor to serve as a guide for participants to attain the appropriate intensity.

Group Type EXPERIMENTAL

Moderate Exercise Group

Intervention Type BEHAVIORAL

Participants will be required to walk briskly (equivalent to moderate intensity) on a treadmill for 10 minutes.

Passive Sitting Group

The passive sitting condition will involve participants sitting passively for 10 minutes on a chair. Heart rate (HR) will be monitored in participants of the passive sitting group to help maintain group equivalency (with the moderate exercise condition) in regards to distraction effects and researcher contact.

Group Type ACTIVE_COMPARATOR

Passive Sitting Group

Intervention Type BEHAVIORAL

Participants will be required to sit passively for 10 minutes on a chair.

Interventions

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Moderate Exercise Group

Participants will be required to walk briskly (equivalent to moderate intensity) on a treadmill for 10 minutes.

Intervention Type BEHAVIORAL

Passive Sitting Group

Participants will be required to sit passively for 10 minutes on a chair.

Intervention Type BEHAVIORAL

Other Intervention Names

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Physical activity Sedentary

Eligibility Criteria

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Inclusion Criteria

* 18 to 64 years of age
* Smoke 10 cigarettes or more per day
* Not have any medical condition that is contraindicative for exercise
* Not be pregnant or intending on being pregnant over the course of the study
* Be able to read and write in English
* Have a telephone or an email account so that they can be contacted
* Completed the Physical Activity Readiness Questionnaire (PAR-Q)
* Have Medical Doctor's clearance if they answer "YES" to one or more questions on the Physical Activity Readiness Questionnaire (PAR-Q)
* Have not been engaged in a serious quit attempt in the last six months
* Have been smoking for more than 2 years
* Must not be suffering from an illness (e.g. cold) that would affect their typical smoking behaviour

Exclusion Criteria

* Contraindication to exercise (e.g., disability, unstable angina)
* On medication for physical and/or mental health reasons that would make compliance with the study protocol difficult or dangerous
* Have substance dependency problems (e.g., alcohol)
* Are pregnant
* Be younger than 18 years of age
* Be 64 years or older prior to completion of the study
* Have been engaged in a serious quit attempt in the last six months
* Have been smoking for less than 2 years
* Suffering from an illness (e.g. cold) that would affect their typical smoking behaviour
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Western Ontario, Canada

OTHER

Sponsor Role lead

Responsible Party

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Harry Prapavessis

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Harry Prapavessis, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Western University, Canada

Locations

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Exercise and Health Psychology Laboratory- University of Western Ontario

London, Ontario, Canada

Site Status

Countries

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Canada

References

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Aveyard P, West R. Managing smoking cessation. BMJ. 2007 Jul 7;335(7609):37-41. doi: 10.1136/bmj.39252.591806.47. No abstract available.

Reference Type BACKGROUND
PMID: 17615224 (View on PubMed)

Ussher MH, Taylor A, Faulkner G. Exercise interventions for smoking cessation. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD002295. doi: 10.1002/14651858.CD002295.pub3.

Reference Type BACKGROUND
PMID: 18843632 (View on PubMed)

Taylor AH, Ussher MH, Faulkner G. The acute effects of exercise on cigarette cravings, withdrawal symptoms, affect and smoking behaviour: a systematic review. Addiction. 2007 Apr;102(4):534-43. doi: 10.1111/j.1360-0443.2006.01739.x.

Reference Type BACKGROUND
PMID: 17286639 (View on PubMed)

Taylor A, Katomeri M. Walking reduces cue-elicited cigarette cravings and withdrawal symptoms, and delays ad libitum smoking. Nicotine Tob Res. 2007 Nov;9(11):1183-90. doi: 10.1080/14622200701648896.

Reference Type BACKGROUND
PMID: 17978993 (View on PubMed)

Zacny JP, Stitzer ML. Effects of smoke deprivation interval on puff topography. Clin Pharmacol Ther. 1985 Jul;38(1):109-15. doi: 10.1038/clpt.1985.143.

Reference Type BACKGROUND
PMID: 4006371 (View on PubMed)

Faulkner GE, Arbour-Nicitopoulos KP, & Hsin A. Cutting down one puff at a time: The acute effects of exercise on smoking behavior. Journal of Smoking Cessation (5): 130-135, 2010.

Reference Type BACKGROUND

Related Links

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http://www.ehpl.uwo.ca

Exercise and Health Psychology Laboratory

Other Identifiers

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SmokingTopography210

Identifier Type: -

Identifier Source: org_study_id