Applied Relaxation (AR) Technique Versus Its Modified Version for Treating Menopausal Symptoms

NCT ID: NCT01429636

Last Updated: 2011-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2011-12-31

Brief Summary

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The purpose of this study is to demonstrate better efficacy and effectiveness of modified applied relaxation technique over its original version for treating menopausal symptoms.

Detailed Description

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Applied Relaxation (AR) is the most commonly used behavioral methods for treating menopausal symptoms. Many clinical trials reported that the technique effectively improved vasomotor and related symptoms. There is a strong evidence to support its continue use in clinical settings.

However, the original AR technique is too cumbersome. It involves intensive training once a week for 12 consecutive weeks. Each weekly session takes 60 minutes, and subjects are requested to do self-practice at home for at least 15-20 minutes/day. As such, \>25% of recruited subjects drop out from the training course. The investigators have modified the original AR technique by reducing the duration of training to only once, lasting 60 minutes. Participants are requested to do self-practice at home for 15-20 minutes/day as in the original technique. Instead of coming to a weekly class, the investigators use telephone to communicate with the subjects once a week for 12 consecutive weeks. A preliminary study showed all 10 recruited subjects remained in the study (MR; modified relaxation technique) until completion. They all reported dramatic improvement in their vasomotor symptoms.

In this study, the investigators propose to compare our modified version of AR with the original method in a randomized controlled clinical trial. The subjects will be Thai menopausal women with vasomotor symptoms. The main outcomes are the reduction in the MRS score (intensity of hot flushes, night sweats and sleep disturbances) among those who remain in the program at the end of the study (efficacy evaluation). As nearly all patients will remain in the MR group, while \>25% of those in the AR group will be expected to drop out from the study, the investigators should be able to demonstrate a superiority of MR over AR in terms of effectiveness as well.

Conditions

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Hot Flashes Night Sweats Sleep Disturbances

Keywords

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perimenopause postmenopause vasomotor symptoms relaxation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Applied Relaxation (AR)

Group Type EXPERIMENTAL

Applied Relaxation (AR)

Intervention Type BEHAVIORAL

Participants will receive 12 sessions AR training. After that they will asked to practice at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Modified Relaxation (MR)

Group Type EXPERIMENTAL

Modified Relaxation (MR)

Intervention Type BEHAVIORAL

The MR technique is modified from the AR technique that will require participants to attend only 1 session, lasting 60 minutes. After the training session, participants will be given a hand-out on MR. They will continue to practice MR at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Interventions

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Modified Relaxation (MR)

The MR technique is modified from the AR technique that will require participants to attend only 1 session, lasting 60 minutes. After the training session, participants will be given a hand-out on MR. They will continue to practice MR at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Intervention Type BEHAVIORAL

Applied Relaxation (AR)

Participants will receive 12 sessions AR training. After that they will asked to practice at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Intervention Type BEHAVIORAL

Other Intervention Names

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Behavioral relaxation Behavioral Applied Relaxation

Eligibility Criteria

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Inclusion Criteria

* Perimenopausal women and postmenopausal women with either surgical or spontaneous menopause.
* Women who have at least 5 points of MRS score.

Exclusion Criteria

* Women who are taking any hormone therapy for any reason in the past three months prior to entering the trails.
* Women with uncontrolled hypertension (\>95mmHg diastolic pressure) or daily use of sedatives, tranquilizer or antidepressant medication.
Minimum Eligible Age

45 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Chiang Mai University

OTHER

Sponsor Role lead

Responsible Party

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Suprawita Saensak

Phase 3 Study of Applied Relaxation (AR) Technique versus Its Modified Version for Treating Menopausal Symptoms.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Suprawita - Saensak, PhDcandidate

Role: PRINCIPAL_INVESTIGATOR

PhD in Clinical Epidemiology Program, Faculty of Medicine, Chiang Mai University (Thailand)

Locations

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Mahassarakham Hospital

Maha Sarakham, Northeast, Thailand

Site Status

Countries

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Thailand

Related Links

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http://www.nih.gov

NIH is the nation's medical research agency-supporting scientific studies that turn discovery into health.

http://www.ncbi.nlm.nih.gov/pubmed

PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books.

http://www.elsevier.com

Elsevier is committed to making genuine contributions to the science and health communities.

http://www.menopause.org

The Journal of The North American Menopause Society is a peer-reviewed scientific journal owned by NAMS and published by Lippincott Williams \& Wilkins (LWW).

http://www.aepc.es/ijchp

The International Journal of Clinical and Health Psychology.

http://www.springer.com/medicine/journal

The world's largest collection of STM books, journals, protocol and reference works.

Other Identifiers

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ARMR-Sympts

Identifier Type: -

Identifier Source: org_study_id