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Berlin Beat of Running Study

NCT ID: NCT01428778

Last Updated: 2016-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-09-30

Study Completion Date

2012-09-30

Brief Summary

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This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.

Detailed Description

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Up to 120 experienced marathon runners will participate in the "Berlin Beat of Running Study" and will wear a transportable electrocardiogram (ECG) recorder at least 24 hours before, during and 24 hours after the BMW-Berlin Marathon. All participants will undergo brain MRI examinations to detect cerebral lesions within days before and after the marathon race, respectively. Moreover, serial blood samples will be taken a few days before, immediately after as well as a few days after the BMW-Berlin Marathon.

Conditions

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Cardiac Arrhythmia Brain Lesion Stroke

Keywords

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Marathon running Brain MRI ECG recording Blood tests

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 35-65 years
* at least 2 marathon runs within the last 5 years
* weekly running of at least 40 km

Exclusion Criteria

* Known cardiac arrhythmia or prior stroke
* contraindication for MRI.
Minimum Eligible Age

35 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Center for Stroke Research Berlin

OTHER

Sponsor Role collaborator

Medical Institute BMW-Berlin Marathon, Berlin, Germany

UNKNOWN

Sponsor Role collaborator

Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Karl Georg Haeusler

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karl Georg Haeusler, MD

Role: PRINCIPAL_INVESTIGATOR

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Germany.

Matthias Endres, MD

Role: STUDY_CHAIR

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Germany

Wilhelm Haverkamp, MD

Role: STUDY_CHAIR

Departement of Cardiology, Campus Virchow, Charité - Universitätsmedizin Berlin, Germany

Matthias Kruell, MD

Role: STUDY_CHAIR

Medical Institute BMW-Berlin Marathon

Peter U Heuschmann, MD

Role: STUDY_CHAIR

Center for Stroke Research Berlin

Gerhard Jan Jungehuelsing, MD

Role: PRINCIPAL_INVESTIGATOR

Center for Stroke Research Berlin

Locations

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Center for Stroke Research Berlin

Berlin, , Germany

Site Status

Countries

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Germany

References

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Herm J, Topper A, Wutzler A, Kunze C, Krull M, Brechtel L, Lock J, Fiebach JB, Heuschmann PU, Haverkamp W, Endres M, Jungehulsing GJ, Haeusler KG. Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study. BMJ Open. 2017 Aug 3;7(8):e015798. doi: 10.1136/bmjopen-2016-015798.

Reference Type DERIVED
PMID: 28775185 (View on PubMed)

Haeusler KG, Herm J, Kunze C, Krull M, Brechtel L, Lock J, Hohenhaus M, Heuschmann PU, Fiebach JB, Haverkamp W, Endres M, Jungehulsing GJ. Rate of cardiac arrhythmias and silent brain lesions in experienced marathon runners: rationale, design and baseline data of the Berlin Beat of Running study. BMC Cardiovasc Disord. 2012 Aug 31;12:69. doi: 10.1186/1471-2261-12-69.

Reference Type DERIVED
PMID: 22938148 (View on PubMed)

Other Identifiers

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EA4/042/11

Identifier Type: OTHER

Identifier Source: secondary_id

Berlin Beat

Identifier Type: -

Identifier Source: org_study_id