ALK21-025: Vivitrol's Cost and Treatment Outcomes Registry

NCT ID: NCT01422837

Last Updated: 2018-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

403 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2013-10-31

Brief Summary

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The objective of the VIVITROL Registry is to gather real world data on opioid dependence and to provide understanding of the health economics of opioid dependence.

Detailed Description

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The VIVITROL Registry is an observational, open-label, single-arm, multi-center registry of patients who have initiated treatment with VIVITROL for prevention of relapse to opioid dependence, following opioid detoxification.

The objectives of the VIVITROL Registry are:

* To describe characteristics of patients receiving VIVITROL for opioid dependence in real-world clinical practice.
* To assess clinical, health economic, and health-related quality of life (HRQOL) outcomes in a broad population of patients receiving VIVITROL in real-world clinical practice.
* To provide additional data to inform future research on VIVITROL.

Patients 18 years of age or older who have been determined by their participating prescriber to be an appropriate candidate for VIVITROL treatment may be offered enrollment into the registry. The decision to treat a patient with VIVITROL will be made by the patient's participating prescriber independent of the registry. VIVITROL will not be provided to patients enrolled in the registry in exchange for their participation; patients will receive commercially available VIVITROL via a standard prescription that will be filled through standard commercial channels.

Patients will be observed while receiving VIVITROL and for six months after they discontinue VIVITROL use. The registry is non-interventional; it will neither direct the treatment plan for enrolled patients nor define the frequency of follow-up visits of each patient. A patient's participation in the registry will not influence or direct patient treatment procedures or follow-up care. It is expected that patients will be seen at least once per month during active VIVITROL treatment to receive their monthly injection.

During the standard monthly injection visits, patients will be asked to provide detailed health economics information using a variety of questionnaires, including the EQ-5D and SF-12v2.

Conditions

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Opioid Dependence

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patient is aged 18 years or older
* Patient is diagnosed with a current opioid dependence for which treatment with VIVITROL is being initiated
* Patient has provided written informed consent
* Patient is willing and able to provide the information to be collected via the registry's interviews and questionnaires
* Patient expects to be available for ongoing registry participation

Exclusion Criteria

* Prior use of VIVITROL
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alkermes, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alkermes Medical Director

Role: STUDY_DIRECTOR

Alkermes, Inc.

Locations

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Assisted Recovery Centers of America

Phoenix, Arizona, United States

Site Status

Arkansas Psychiatric Clinc

Little Rock, Arkansas, United States

Site Status

Amy Solomon, MD

Ben Lomond, California, United States

Site Status

Touchstone Medical Group

Clovis, California, United States

Site Status

Kenneth C. Russ, MD

Palm Springs, California, United States

Site Status

Tarzana Treatment Centers

Tarzana, California, United States

Site Status

The NeuroBehavioral Institute of Colorado, PC

Lone Tree, Colorado, United States

Site Status

Psychotherapy Services, Etc.

Groton, Connecticut, United States

Site Status

Jacqueline Boutrouille, MD

Tamarac, Florida, United States

Site Status

Alliance Clinical Research

Winter Park, Florida, United States

Site Status

Atlanta Institute of Medicine and Research

Atlanta, Georgia, United States

Site Status

PACT Atlanta

Decatur, Georgia, United States

Site Status

Gosnold-Thorne Counseling Center

Centerville, Massachusetts, United States

Site Status

Dr. Li's Clinic

Milford, Massachusetts, United States

Site Status

Assisted Recovery Centers of America

St Louis, Missouri, United States

Site Status

Dent Neurologic Institute

Amherst, New York, United States

Site Status

Dr. Michael Sanders

Great Neck, New York, United States

Site Status

Fakhouri Medical

Hopewell Junction, New York, United States

Site Status

Parallax Center

New York, New York, United States

Site Status

Healing Comfort Clinic

Corvallis, Oregon, United States

Site Status

Jasper Health

Media, Pennsylvania, United States

Site Status

Institute of Addiction Medicine

Plymouth Meeting, Pennsylvania, United States

Site Status

Innovation Laboratory/PEARL

Johnson City, Tennessee, United States

Site Status

Urschel Recovery Science Institute

Dallas, Texas, United States

Site Status

Holiner Psychiatric Group

Dallas, Texas, United States

Site Status

Lenae White, MD, PA

Dallas, Texas, United States

Site Status

Utah Addiction Medicine & Counseling

Bountiful, Utah, United States

Site Status

Adolescent and Family Health Center, PC

Midlothian, Virginia, United States

Site Status

Chessen and Associates

Newport News, Virginia, United States

Site Status

Creekside Center for Integrative Medicine

Bellevue, Washington, United States

Site Status

Child and Adolescent Psychiatry

Bothell, Washington, United States

Site Status

Countries

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United States

References

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Saxon AJ, Akerman SC, Liu CC, Sullivan MA, Silverman BL, Vocci FJ. Extended-release naltrexone (XR-NTX) for opioid use disorder in clinical practice: Vivitrol's Cost and Treatment Outcomes Registry. Addiction. 2018 Aug;113(8):1477-1487. doi: 10.1111/add.14199. Epub 2018 Apr 1.

Reference Type RESULT
PMID: 29493836 (View on PubMed)

Other Identifiers

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ALK21-025

Identifier Type: -

Identifier Source: org_study_id

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