Changes of the Peripapillary Retinal Nerve Fiber Layer After Filtration Surgery in Glaucoma Patients
NCT ID: NCT01422525
Last Updated: 2014-12-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
12 participants
OBSERVATIONAL
2011-11-30
Brief Summary
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The aim of this prospective observational case study is to determine changes of the peripapillary retinal nerve fiber layer thickness using spectral domain optical coherence tomography in patients with glaucoma after surgical reduction of intraocular pressure.
Detailed Description
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The main outcome measures will be changes in overall and quadrant RNFL thickness with respect to reduction in intraocular pressure (IOP), correlation between RNFL thickness and alteration in visual field and predictive factors of postoperative IOP-reduction and changes of RNFL thickness.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Trabeculectomy RNFL thickness OCT
spectral domain optical coherence tomography
RNFL thickness measurement using spectral domain optical coherence tomography at baseline, 1, 3 and 6 months postoperatively.
Interventions
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spectral domain optical coherence tomography
RNFL thickness measurement using spectral domain optical coherence tomography at baseline, 1, 3 and 6 months postoperatively.
Eligibility Criteria
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Inclusion Criteria
* target intraocular pressure under medical treatment was not reached
* progression of visual loss
* best corrected visual acuity of 20/100 or more
* spherical equivalent refraction of -8.0 to +4.0 D
* perimetry: less than 20% false positive answers
Exclusion Criteria
* congenital glaucoma
* normal tension glaucoma
* neovascular glaucoma
18 Years
ALL
No
Sponsors
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University Eye Hospital, Würzburg
OTHER
Responsible Party
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Juliane Matlach, MD
Dr.
Locations
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University Eye Hospital Wuerzburg
Würzburg, Bavaria, Germany
Countries
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Other Identifiers
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OCT-TET
Identifier Type: -
Identifier Source: org_study_id