Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
84 participants
OBSERVATIONAL
2011-08-31
2014-08-31
Brief Summary
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The main objective of this study is to determine endomicroscopic features of mucosal healing in patients with IBD.
Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Crohn´s disease - active
Patients with Crohn´s disease in the active phase.
Endomicroscopy
Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.
Crohn´s disease - quiescent
Patients with Crohn´s disease in the quiescent phase.
Endomicroscopy
Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.
Ulcerative colitis - active
Patients with ulcerative colitis in the active stage.
Endomicroscopy
Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.
Ucerative colitis - quiescent
Patients with ulcerative colitis in the quiescent stage.
Endomicroscopy
Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.
Interventions
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Endomicroscopy
Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.
Eligibility Criteria
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Inclusion Criteria
* Age 18-85 years
* Ability of subjects to understand character and individual consequences of clinical trial
* Subjects undergoing colonoscopy
Exclusion Criteria
* Severe Coagulopathy (Prothrombin time \< 50% of control, Partial thromboplastin time \> 50 s)
* Pregnancy or breast feeding
* Active gastrointestinal bleeding
* Residing in institutions (e.g. prison)
* Known allergy against fluorescein
* Proctocolectomy
18 Years
85 Years
ALL
No
Sponsors
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University of Erlangen-Nürnberg Medical School
OTHER
Responsible Party
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Principal Investigators
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Helmut Neumann, Professor
Role: PRINCIPAL_INVESTIGATOR
Department of Medicine I, University of Erlangen-Nuremberg, Germany
Markus F. Neurath, Professor
Role: PRINCIPAL_INVESTIGATOR
Department of Medicine I, University of Erlangen-Nuremberg, Germany
Locations
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University of Erlangen-Nuremberg
Erlangen, , Germany
Countries
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Other Identifiers
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HN-0008
Identifier Type: -
Identifier Source: org_study_id