Trial Outcomes & Findings for Electrode-based Sensor for Non-invasive Fetal Heart Rate and EMG Monitoring With Improved Reliability (NCT NCT01400880)

NCT ID: NCT01400880

Last Updated: 2015-02-12

Results Overview

Contraction timing as measured by the electrode sensor and contraction timing as measure by the TOCO, both compared to the contraction timing as measured by the IUPC gold standard. The contraction timing values of the electrode sensor and TOCO were then compared.

Recruitment status

COMPLETED

Target enrollment

103 participants

Primary outcome timeframe

Stage I and II Labor

Results posted on

2015-02-12

Participant Flow

Participant milestones

Participant milestones
Measure
Electrode Sensor, TOCO and IUPC
Pregnant women between the ages of 18-50 with a single viable fetus in cephalic presentation monitored with Electrode Sensor, TOCO and IUPC
Overall Study
STARTED
103
Overall Study
COMPLETED
101
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Electrode-based Sensor for Non-invasive Fetal Heart Rate and EMG Monitoring With Improved Reliability

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Primary
n=101 Participants
Pregnant women between the ages of 18-50 with a single viable fetus in cephalic presentation
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
101 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex/Gender, Customized
Pregnant Women
101 participants
n=5 Participants

PRIMARY outcome

Timeframe: Stage I and II Labor

Population: Pregnant women between the ages of 18-50 with a single viable fetus in stages I and/or II of labor

Contraction timing as measured by the electrode sensor and contraction timing as measure by the TOCO, both compared to the contraction timing as measured by the IUPC gold standard. The contraction timing values of the electrode sensor and TOCO were then compared.

Outcome measures

Outcome measures
Measure
Electrode Sensor, TOCO and IUPC
n=101 Participants
Pregnant women between the ages of 18-50 with a single viable fetus in cephalic presentation studied with electrode sensor, Tocodynamometer and IUPC
Comparison of Electrode Sensor and TOCO Detection of Contraction Events, as Compared to IUPC
TOCO patient group
2.98 seconds
Standard Deviation 3.28
Comparison of Electrode Sensor and TOCO Detection of Contraction Events, as Compared to IUPC
Electrode Sensor patient group
3.95 seconds
Standard Deviation 2.65

Adverse Events

Primary

Serious events: 0 serious events
Other events: 15 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Primary
n=103 participants at risk
Pregnant women between the ages of 18-50 with a single viable fetus in cephalic presentation
Infections and infestations
Chorioamnionitis
12.6%
13/103 • Number of events 13 • Adverse events occurred throughout the study dates starting 8/1/11 and ending 4/25/13. 1 year 9 months.
All adverse events were recorded, even if the event was not directly related to the study. Some patients developed infection directly after data collection started and thus were already infected, not being caused by the study. Also, C-sections were reported as it disrupted the data collection and was not a foreseeable event.
Surgical and medical procedures
c-section
1.9%
2/103 • Number of events 2 • Adverse events occurred throughout the study dates starting 8/1/11 and ending 4/25/13. 1 year 9 months.
All adverse events were recorded, even if the event was not directly related to the study. Some patients developed infection directly after data collection started and thus were already infected, not being caused by the study. Also, C-sections were reported as it disrupted the data collection and was not a foreseeable event.

Additional Information

Dr. Tony Gregg

University of Florida

Phone: 352-265-0111

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place