Effects of Inspiratory Muscle Training in COPD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

208 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2016-12-31

Brief Summary

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The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

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Detailed Description

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Conditions

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COPD Inspiratory Muscle Weakness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Inspiratory Muscle Training

Group Type EXPERIMENTAL

Inspiratory Muscle Training

Intervention Type PROCEDURE

Three times daily inspiratory muscle training (2x30 breaths) at an intensity of \>50% Pi,max

Sham IMT

Sham Inspiratory Muscle Training

Group Type PLACEBO_COMPARATOR

Inspiratory Muscle Training

Intervention Type PROCEDURE

Three times daily inspiratory muscle training (2x30 breaths) at an intensity of \>50% Pi,max

Interventions

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Inspiratory Muscle Training

Three times daily inspiratory muscle training (2x30 breaths) at an intensity of \>50% Pi,max

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with COPD
* Eligible to participate in a exercise training intervention of 8 weeks
* Pi,max \<60cmH2O or \<50% of the predicted normal value