Canadian Humira Post Marketing Observational Epidemiological Study: Assessing Effectiveness in Ankylosing Spondylitis
NCT ID: NCT01387802
Last Updated: 2020-12-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
722 participants
OBSERVATIONAL
2011-06-29
2019-12-16
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Non-Biologic arm
Patients that have not responded to the current treatment with an NSAID (Nonsteroidal Anti-Inflammatory Drug) and/or non - biologic DMARD (Disease-Modifying Anti Rheumatic Drug) for peripheral joint involvement and switch to or addition of another NSAID /DMARDS
No interventions assigned to this group
Biologic arm
Patients that have not responded to the current treatment with non biologic DMARDS (Disease-Modifying Anti Rheumatic Drug) /NSAID (Nonsteroidal Anti-Inflammatory Drug) and switch to or addition of adalimumab
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Has provided written informed consent allowing the use of their data for the study and providing permission for contact by the study personnel
* Active Ankylosing Spondylitis as per the judgment of the treating physician
* Inadequate response or non tolerant to current NSAID (Nonsteroidal Anti-Inflammatory Drug) or DMARD (Disease-Modifying Anti Rheumatic Drug) based treatment for AS
Exclusion Criteria
* Patient cannot or will not sign informed consent
* Stable disease with adequate tolerance and response to current treatment and no change in treatment is indicated
* Previous treatment with anti-TNF (Tumor Necrosis Factor) or other biologic agent
* Presence of other condition that, in the opinion of the treating physician, prohibits the patient from participating in the study or obscures the assessment of the treatment of AS
18 Years
99 Years
ALL
No
Sponsors
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JSS Medical Research Inc.
INDUSTRY
Cato Research
INDUSTRY
AbbVie (prior sponsor, Abbott)
INDUSTRY
Responsible Party
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Principal Investigators
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AbbVie Inc.
Role: STUDY_DIRECTOR
AbbVie
Locations
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Rheumatology Clinic /ID# 54768
Calgary, Alberta, Canada
Associate Clinic /ID# 64274
Calgary, Alberta, Canada
Pont, Cranbrook, BC, CA /ID# 55242
Cranbrook, British Columbia, Canada
Dr. Barbara T. Blumenauer Inc. /ID# 55226
Kamloops, British Columbia, Canada
Hudson, Kamloops, Canada /ID# 54577
Kamloops, British Columbia, Canada
Dr. Maqbool R. Sheriff Inc. /ID# 55247
Nanaimo, British Columbia, Canada
Stewart, Penticton, CA /ID# 67096
Penticton, British Columbia, Canada
Dr. Michael Buchanan, Inc. /ID# 55227
Prince George, British Columbia, Canada
Dr. J. Antonio Avina-Zubieta /ID# 68263
Richmond, British Columbia, Canada
Dr. Alfonso Verdejo Inc. /ID# 54572
Vancouver, British Columbia, Canada
Dr. Milton F. Baker Inc. /ID# 55197
Victoria, British Columbia, Canada
Manitoba Clinic /ID# 54580
Winnipeg, Manitoba, Canada
Bulleid Henderson Prof. Corp. /ID# 55256
Fredericton, New Brunswick, Canada
Ecker, Fredericton, CA /ID# 54748
Fredericton, New Brunswick, Canada
Nexus Clinical Research /ID# 54757
St. John's, Newfoundland and Labrador, Canada
St. Clare's Mercy Hospital /ID# 54767
St. John's, Newfoundland and Labrador, Canada
Qe Ii Hsc /Id# 55261
Halifax, Nova Scotia, Canada
Dr. Juris Lazovskis Inc. /ID# 61562
Sydney, Nova Scotia, Canada
Pavlova, Hamilton, CA /ID# 65011
Ancaster, Ontario, Canada
Waterside Clinique /ID# 72174
Barrie, Ontario, Canada
Joshi, Brampton, Canada /ID# 54758
Brampton, Ontario, Canada
Brockville Medical Center /ID# 65502
Brockville, Ontario, Canada
Dr. Sanjay Dixit Medicine Professional Corporation /ID# 67347
Burlington, Ontario, Canada
Aviva Clinical Trial Group /ID# 54764
Burlington, Ontario, Canada
Dr. Chrisotomor Kouroukis & Dr /ID# 137831
Dundas, Ontario, Canada
Charlton Medical Centre /ID# 133072
Hamilton, Ontario, Canada
Charlton Medical Centre /ID# 55417
Hamilton, Ontario, Canada
Dr. William G. Bensen Centre /ID# 54762
Hamilton, Ontario, Canada
West Mountain Medical Center /ID# 128877
Hamilton, Ontario, Canada
KW Musculoskeletal Research /ID# 70093
Kitchener, Ontario, Canada
Brandusa Florica Med Prof Corp /ID# 81877
Mississauga, Ontario, Canada
Montgomery, Mississauga, CA /ID# 54581
Mississauga, Ontario, Canada
Credit Valley Rheumatology /ID# 54750
Mississauga, Ontario, Canada
Imtiaz MS Khan Medicine Prof /ID# 55401
Mississauga, Ontario, Canada
Morassut, Nepean, Canada /ID# 55410
Nepean, Ontario, Canada
The Arthritis Program Res Grp /ID# 54755
Newmarket, Ontario, Canada
Rajwinder S. Dhillon Medicine /ID# 138671
Niagara Falls, Ontario, Canada
Kapur, Ottawa, Canada /ID# 55397
Ottawa, Ontario, Canada
Davis, Ottawa, CA /ID# 55296
Ottawa, Ontario, Canada
Setty, Owen Sound, CA /ID# 54583
Owen Sound, Ontario, Canada
Niagara Peninsula Arthritis Ct /ID# 67282
St. Catharines, Ontario, Canada
Pedvis Med Prof Corp /ID# 55411
Toronto, Ontario, Canada
Hamilton, Toronto, CA /ID# 54575
Toronto, Ontario, Canada
Jonathan Stein Med Prof Corp /ID# 55451
Toronto, Ontario, Canada
Karasik, Toronto, CA /ID# 54751
Toronto, Ontario, Canada
Dr. Samuel K Silverberg /ID# 55449
Toronto, Ontario, Canada
Ctr de Med Sportive de Laval /ID# 54576
Laval, Quebec, Canada
Institut de Rhum. de Montreal /ID# 54761
Montreal, Quebec, Canada
Jewish General Hospital /ID# 63655
Montreal, Quebec, Canada
PSS Medical Inc. /ID# 54754
Montreal, Quebec, Canada
Couture, Outremont, CA /ID# 54574
Outremont, Quebec, Canada
Ctr. de Rheum de l'est du QC /ID# 54765
Rimouski, Quebec, Canada
Clinique Medicale Langelier /ID# 55460
Saint-Léonard, Quebec, Canada
Groupe de Recherche en Maladies Osseuses /ID# 45623
Sainte-Foy, Quebec, Canada
Ctr. de Recherche Musculo-Sque /ID# 55469
Trois-Rivières, Quebec, Canada
Rheum Disease Ctr of Montreal /ID# 143963
Westmount, Quebec, Canada
Countries
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Related Links
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clinical study report synopsis
Other Identifiers
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P12-672
Identifier Type: -
Identifier Source: org_study_id