Trial Outcomes & Findings for European Survey: Risk of Cyanide Poisoning in Smoke Inhalation (NCT NCT01386788)

NCT ID: NCT01386788

Last Updated: 2016-09-28

Results Overview

Number of participants who survived at 24 hours after smoke inhalation were reported.

Recruitment status

COMPLETED

Target enrollment

102 participants

Primary outcome timeframe

24 hours

Results posted on

2016-09-28

Participant Flow

102 patients were enrolled, data of 100 patients were evaluated

Participant milestones

Participant milestones
Measure
Smoke Inhalation Victims
Smoke inhalation victims included civil victims and fire workers as specified in the inclusion criteria were observed.
Overall Study
STARTED
102
Overall Study
COMPLETED
100
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Reasons for withdrawal
Measure
Smoke Inhalation Victims
Smoke inhalation victims included civil victims and fire workers as specified in the inclusion criteria were observed.
Overall Study
Lost to Follow-up
2

Baseline Characteristics

European Survey: Risk of Cyanide Poisoning in Smoke Inhalation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Smoke Inhalation Victims
n=102 Participants
Smoke inhalation victims included civil victims and fire workers as specified in the inclusion criteria were observed.
Age, Continuous
49.4 years
FULL_RANGE 19 • n=93 Participants
Sex: Female, Male
Female
39 Participants
n=93 Participants
Sex: Female, Male
Male
63 Participants
n=93 Participants

PRIMARY outcome

Timeframe: 24 hours

Number of participants who survived at 24 hours after smoke inhalation were reported.

Outcome measures

Outcome measures
Measure
Smoke Inhalation Victims
n=102 Participants
Smoke inhalation victims included civil victims and fire workers as specified in the inclusion criteria were observed.
Overall Survival After 24 Hours
96 participants

PRIMARY outcome

Timeframe: blood sampling within 2 hours after smoke inhalation

Population: All recruited patients that met all inclusion criteria including blood sampling for cyanide serum level

Outcome measures

Outcome measures
Measure
Smoke Inhalation Victims
n=100 Participants
Smoke inhalation victims included civil victims and fire workers as specified in the inclusion criteria were observed.
Serum Cyanide Levels
<1.1 mcmol/l
25 participants
Serum Cyanide Levels
1.2 - 5 mcmol/l
49 participants
Serum Cyanide Levels
>5 - 10 mcmol/l
5 participants
Serum Cyanide Levels
>10- 20 mcmol/l
7 participants
Serum Cyanide Levels
>20- 40 mcmol/l
4 participants
Serum Cyanide Levels
>40- 100 mcmol/l
7 participants
Serum Cyanide Levels
>100 mcmol/l
3 participants

Adverse Events

Smoke Inhalation Victim

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Ernst Koch

EKoch

Phone: ++49 6257 1788

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place