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Neighborhoods, Networks, Depression, and HIV Risk

NCT ID: NCT01380613

Last Updated: 2013-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

965 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2013-07-31

Brief Summary

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The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.

Detailed Description

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This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.

Conditions

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HIV Depression Drug Use

Keywords

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HIV depression drug use, risk reduction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Workshop Control

Participants receive HIV/STDs risk reduction information.

Group Type ACTIVE_COMPARATOR

Workshop control

Intervention Type BEHAVIORAL

1 session intervention on standard HIV/STD information

Intervention Workshop

Participants learn skills to cope with depressive symptoms and stress as well as safer sex and injection skills.

Group Type EXPERIMENTAL

Workshop

Intervention Type BEHAVIORAL

10 session intervention

Interventions

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Workshop

10 session intervention

Intervention Type BEHAVIORAL

Workshop control

1 session intervention on standard HIV/STD information

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. 18-55 years old
2. HIV Risk Behavior:

3a. Injected drugs more than 3 times in the past week OR

3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+

4\. Willingness to attend group sessions

Exclusion Criteria

1. Enrolled in another HIV behavioral intervention or depression study in past the 3 years
2. Enrolled in another Lighthouse study in past the 5 years
3. Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current project.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Johns Hopkins Bloomberg School of Public Health

OTHER

Sponsor Role lead

Responsible Party

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Carl Latkin

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Carl A Latkin, PhD

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins Bloomberg School of Public Health

Locations

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Lighthouse Studies @ Peer Points- JHSPH

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Tobin K, Davey-Rothwell MA, Nonyane BAS, Knowlton A, Wissow L, Latkin CA. RCT of an integrated CBT-HIV intervention on depressive symptoms and HIV risk. PLoS One. 2017 Dec 14;12(12):e0187180. doi: 10.1371/journal.pone.0187180. eCollection 2017.

Reference Type DERIVED
PMID: 29240757 (View on PubMed)

Other Identifiers

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R01DA022961

Identifier Type: NIH

Identifier Source: secondary_id

View Link

DESPR-DA022961-03

Identifier Type: -

Identifier Source: org_study_id