CORAL Study: Proof of Concept Trial

NCT ID: NCT01379014

Last Updated: 2011-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-07-31

Study Completion Date

2013-03-31

Brief Summary

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A decision aid tool (DAT) to assist mental health service users in reaching disclosure decisions in the context of employment was developed in a previous study (IRAS REC ref: 07/Q0706/21). The initial feasibility and acceptability was assessed in a group of 15 mental health service users with mean decisional conflict scores reduced from 51.98 to 35.52 after completion. 60% of participants reported that the DAT was quick to complete, 40% that it was easy, 60% that it was relevant and 80% that they would definitely or probably use it in making disclosure decisions. This current study (CORAL: Proof of concept RCT) aims to determine whether a full randomised controlled trial of the DAT is justifiable and feasible, and to optimise its design. This will consider: 1) effects of the intervention; 2) baseline predictors of disclosure; and 3) exploration of the relationship between use of the DAT and the rate of disclosure.

Eighty people who are on the caseload of a vocational specialist working with people with mental illness will be included in this study. All participants will be receiving treatment from an Improving Access to Psychological Therapies (IAPT) service or a Community Mental Health Team (CMHT). An equal number from each group will be allocated to receive either the DAT intervention or treatment as usual. Individuals from both groups will complete baseline assessment and 3month followup assessments. Those allocated to the intervention will also complete an assessment immediately following the intervention. Qualitative interviews will also be conducted at 3 months with a maximum of 15 people from the intervention group and 6 people from the control group.

Detailed Description

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The principal aims are to determine whether a full randomised controlled trial of the CORAL decision aid tool is justifiable and feasible and to optimise its design. Specific objectives are as follows:

1. To examine the effect of the DAT on decisional conflict regarding disclosure both immediately and at 3 months post first use.
2. To collect data to inform sample size calculations for the primary outcome measures for use in a future full scale trial(gaining employment and workplace accommodations).
3. To test study procedures, including the sample that can be drawn using the inclusion and exclusion criteria; the full time equivalent needed for research assistants to recruit sufficient numbers and carry out the study procedures in the time available; and whether the measure leads to too much respondent burden.
4. To pilot the use of a questionnaire on employment and disclosure related activities.
5. To test the selected randomisation method, in this case individual level randomisation, including the methods for avoiding and measuring contamination.
6. To pilot recruitment and retention methods for service users and vocational specialists.
7. To estimate effect sizes and their confidence intervals for employment related activities (proxy outcome measures for gaining employment and workplace accommodations), in order to determine whether a full scale trial is justified.
8. To modify the conceptual model

Conditions

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Mental Illness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Investigators

Study Groups

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Decision Aid Tool

Intervention group - receives the decision aid tool in booklet form and is introduced to it by an investigator.

Group Type EXPERIMENTAL

Decision Aid Tool

Intervention Type BEHAVIORAL

A booklet which outlines to pros and cons of different decision outcomes, and is designed to assist the user in making a decision according to their own specific circumstances

Control

The control group does not receive a copy of the decision aid tool booklet, instead received treatment as usual from vocational specialist

Group Type NO_INTERVENTION

Treatment as Usual

Intervention Type OTHER

The control group does not receive a copy of the decision aid tool booklet, instead received treatment as usual from vocational specialist

Interventions

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Decision Aid Tool

A booklet which outlines to pros and cons of different decision outcomes, and is designed to assist the user in making a decision according to their own specific circumstances

Intervention Type BEHAVIORAL

Treatment as Usual

The control group does not receive a copy of the decision aid tool booklet, instead received treatment as usual from vocational specialist

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. On the caseload of a vocational specialist working with people with mental illness.
2. Referred to the adviser either from an Increased Access to Psychological Therapies or secondary mental health care service.
3. Aged 18 years or older
4. Currently seeking either paid or voluntary employment or interested in seeking paid or voluntary employment
5. Decisional conflict scale score of 37.5 or greater and stage of decision score 1-5

Exclusion Criteria

1. Insufficient English to use the decision aid tool
2. Lack of capacity to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institute of Psychiatry, London

OTHER

Sponsor Role lead

Responsible Party

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Claire Henderson, MRCPsych MSc PhD

Dr Claire Henderson

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Graham Thornicroft, FRCPsych

Role: STUDY_DIRECTOR

Institute of Psychiatry, London

Locations

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Institute of Psychiatry, King's College London

London, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Claire Henderson, MRCPsych

Role: CONTACT

02078485075

References

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Henderson C, Brohan E, Clement S, Williams P, Lassman F, Schauman O, Dockery L, Farrelly S, Murray J, Murphy C, Slade M, Thornicroft G. Decision aid on disclosure of mental health status to an employer: feasibility and outcomes of a randomised controlled trial. Br J Psychiatry. 2013 Nov;203(5):350-7. doi: 10.1192/bjp.bp.113.128470. Epub 2013 Sep 26.

Reference Type DERIVED
PMID: 24072755 (View on PubMed)

Henderson C, Brohan E, Clement S, Williams P, Lassman F, Schauman O, Murray J, Murphy C, Slade M, Thornicroft G. A decision aid to assist decisions on disclosure of mental health status to an employer: protocol for the CORAL exploratory randomised controlled trial. BMC Psychiatry. 2012 Aug 31;12:133. doi: 10.1186/1471-244X-12-133.

Reference Type DERIVED
PMID: 22938019 (View on PubMed)

Other Identifiers

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11/EE/0156

Identifier Type: -

Identifier Source: org_study_id