Identifying Vitamin D Deficiency in Very Low Birth Weight Infant (VLBW) Infants Part 2

NCT ID: NCT01363167

Last Updated: 2014-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2013-10-31

Brief Summary

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This study is to determine the amount of vitamin D required for a very low birth weight infant to reach vitamin D sufficiency and achieve optimal calcium health and bone growth.

Detailed Description

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Conditions

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Infant, Very Low Birth Weight Calcium Deficiency Vitamin D Deficiency

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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400 IU Cholecalciferol - Vitamin D

Group Type ACTIVE_COMPARATOR

400 IU Cholecalciferol- Vitamin D Daily

Intervention Type DIETARY_SUPPLEMENT

Infants who are defined as vitamin D deficient at birth will be randomized to receive either 400 IU vitamin D/day or placebo daily until term age is reached.

Placebo

Placebo contains Fractionated Coconut Oil

Group Type PLACEBO_COMPARATOR

400 IU Cholecalciferol- Vitamin D Daily

Intervention Type DIETARY_SUPPLEMENT

Infants who are defined as vitamin D deficient at birth will be randomized to receive either 400 IU vitamin D/day or placebo daily until term age is reached.

Interventions

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400 IU Cholecalciferol- Vitamin D Daily

Infants who are defined as vitamin D deficient at birth will be randomized to receive either 400 IU vitamin D/day or placebo daily until term age is reached.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Any infant born at the Medical University of South Carolina \<34 weeks gestation
* Less that 1500g at birth
* AGA
* Must be African American or Caucasian
* Each infant born of twin and triplet pregnancies will be eligible

Exclusion Criteria

* Infants with major congenital anomalies or with hemolytic disease requiring exchange transfusion
* Infants born small for-gestational-age (SGA) or large for-gestational-age (LGA)
* Maternal uncontrolled thyroid disease
* Maternal Parathyroid disease
* Infants of races other than African American or Caucasian
Minimum Eligible Age

1 Day

Maximum Eligible Age

3 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Center for Research Resources (NCRR)

NIH

Sponsor Role collaborator

Medical University of South Carolina

OTHER

Sponsor Role lead

Responsible Party

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Sarah N Taylor

Assistant Professor of Pediatrics, Medical University of SC

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sarah N. Taylor, M.D.

Role: PRINCIPAL_INVESTIGATOR

Medical University of South Carolina

Locations

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Medical University of South Carolina

Charleston, South Carolina, United States

Site Status

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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K23RR021891

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HR# 17217

Identifier Type: -

Identifier Source: org_study_id