Safety and Immunogenicity of One Dose of an Inactivated Trivalent Sub-unit Influenza Vaccine Administered to Non-elderly Adult and Elderly Subjects

NCT ID: NCT01357265

Last Updated: 2011-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

125 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2011-06-30

Brief Summary

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This study will evaluate safety and immunogenicity of a sub-unit Influenza vaccine when administered to adult and elderly subjects.

Detailed Description

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Conditions

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Influenza

Keywords

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Seasonal Influenza vaccine

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

No comparator is administered, only one IM single dose of trivalent subunit inactivated influenza vaccine is administered during the vaccination visit

Group Type OTHER

Seasonal Influenza Vaccine

Intervention Type BIOLOGICAL

This phase II is performed as a multicenter study in adult and elderly subjects. Enrolled subjects received one single IM dose of trivalent subunit inactivated flu vaccine during the vaccination visit, according to the study protocol (follow-up period: until day 22) .

Interventions

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Seasonal Influenza Vaccine

This phase II is performed as a multicenter study in adult and elderly subjects. Enrolled subjects received one single IM dose of trivalent subunit inactivated flu vaccine during the vaccination visit, according to the study protocol (follow-up period: until day 22) .

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

Healthy, adult and elderly volunteers over 18 years

Exclusion Criteria

Individuals with any serious chronic or acute disease or known or suspected impairment of the immune system.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Novartis Vaccines

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Dipartimento di Medicina e Scienze dell'Invecchiamento, Università G. D'Annunzio

Via Dei Vestini, Cheiti, Italy

Site Status

Dipartimento di Scienze della Salute Università di Genova

Via Pastore, Genova, Italy

Site Status

Distretto Sanitario di Base di Fossacesia

Via Polidoro-Vasto, Lanciano, Italy

Site Status

ASL Lanciano - Vasto,

Via S. Spaventa, Lanciano, Italy

Site Status

Vaccine and Immunotherapy Research Center Department of Infectious and Tropical Diseases San Raffaele Scientific Institute

Via Stamira d'Ancona, Milano, Italy

Site Status

Dipartimento di malattie infettive Ospedale San Gerardo

Via Pergolesi 33, Monza, Italy

Site Status

Countries

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Italy

Other Identifiers

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2010-024400-98

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

V71_27S

Identifier Type: -

Identifier Source: org_study_id