Analysis of the Enteric Nervous System Using Colonic Biopsies
NCT ID: NCT01353183
Last Updated: 2013-09-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
34 participants
INTERVENTIONAL
2010-11-30
2012-11-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Colonic biopsies
Colonic biopsies obtained during the course of colonoscopy or rectosigmoidoscopy
colonoscopy or rectosigmoidoscopy
Usual procedure
Interventions
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colonoscopy or rectosigmoidoscopy
Usual procedure
Eligibility Criteria
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Inclusion Criteria
* Patients aged 50-80 year old, both genders
* Parkinson's disease patients
* Multiple system atrophy patients
* Progressive supranuclear palsy patients
* Controls: patient at risk of colic cancer for whom a colonoscopy is required
* Patients who signed the informed consent
Controls
* Patients aged 50 to 80 year-old for whom a rectosigmoidoscopy or a colonoscopy is required for colorectal screening
* Patients who signed the informed consent
* Health care beneficiary
Exclusion Criteria
* Colonic disorder (except non-complicated diverticular disease)
* Other neurological disorder than parkinsonism
* Patients treated with either platelet antiaggregants, anticoagulants or with a known coagulation disorder
* Patients with a cognitive impairment that preclude them from understanding the informed consent
* Patients placed under legal guardianship
Controls
* Neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease or other dementia, amyotrophic lateral sclerosis...
* Functional bowel disorder such as irritable bowel syndrome
* Patients with a cognitive impairment that preclude them from understanding the informed consent
50 Years
80 Years
ALL
No
Sponsors
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Nantes University Hospital
OTHER
Responsible Party
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Principal Investigators
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DERKINDEREN Pascal, Professor
Role: PRINCIPAL_INVESTIGATOR
Nantes University Hospital
Locations
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Nantes University Hospital
Nantes, , France
Countries
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Other Identifiers
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ID RCB 2010-A00632-37
Identifier Type: REGISTRY
Identifier Source: secondary_id
10/4-U
Identifier Type: -
Identifier Source: org_study_id