Trial Outcomes & Findings for Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation (NCT NCT01351766)

NCT ID: NCT01351766

Last Updated: 2022-05-18

Results Overview

7 days of smoking abstinence confirmed via expired carbon monoxide at 12 weeks

Recruitment status

COMPLETED

Study phase

PHASE3

Target enrollment

39 participants

Primary outcome timeframe

12 weeks post quit date

Results posted on

2022-05-18

Participant Flow

Participant milestones

Participant milestones
Measure
Behavioral Activation for Smoking
* Eight, 60-minute group sessions over an 8 week period * Eight weeks of transdermal nicotine patch, which will begin at the time of quitting smoking, and will continue after treatment sessions have ended
Overall Study
STARTED
39
Overall Study
COMPLETED
36
Overall Study
NOT COMPLETED
3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Behavioral Activation for Smoking
n=39 Participants
Behavioral Activation for Smoking (BATSY) includes standard smoking cessation strategies and identifying life areas, values, and daily activities to help manage mood. Participants will complete between group exercises and will also monitor and plan daily activities in line with their values. Treatment will be delivered in 8, 60-minute group sessions over an 8-week period. Participants will also be provided 8 weeks of the transdermal nicotine patch. Transdermal Nicotine Patch: 8 weeks of the Transdermal Nicotine Patch Nicoderm CQ at 24 hour doses of 21, 14, and 7 mg respectively depending on participant's initial level of nicotine use. Nicotine patch dose will decrease at 2 or 4 week increments also specific to participant's initial nicotine level.
Age, Categorical
<=18 years
8 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
31 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
20.00 years
STANDARD_DEVIATION 1.32 • n=5 Participants
Sex: Female, Male
Female
12 Participants
n=5 Participants
Sex: Female, Male
Male
27 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
3 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
2 Participants
n=5 Participants
Race (NIH/OMB)
White
31 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
3 Participants
n=5 Participants
Region of Enrollment
United States
39 participants
n=5 Participants

PRIMARY outcome

Timeframe: 12 weeks post quit date

7 days of smoking abstinence confirmed via expired carbon monoxide at 12 weeks

Outcome measures

Outcome measures
Measure
Behavioral Activation for Smoking
n=39 Participants
* Eight, 60-minute group sessions over an 8 week period * Eight weeks of transdermal nicotine patch, which will begin at the time of quitting smoking, and will continue after treatment sessions have ended
Number of Participants Smoking-Abstinent for 7 Days, 12 Weeks Post Quit Date
7 Participants

Adverse Events

Behavioral Activation for Smoking

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Laura MacPherson

University of Maryland

Phone: 6198578425

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place