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Epidemiologic Follow Up Study of Newly Diagnosed Epilepsy Among Seniors

NCT ID: NCT01351727

Last Updated: 2017-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

97 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-31

Study Completion Date

2014-09-30

Brief Summary

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The purpose of this proposed research is to identify individuals in southeastern Arizona aged 65 years and older who have new onset seizures (or newly diagnosed epilepsy) and monitor them for at least two years. In doing so the investigators will be able to describe the public health burden of this condition and to identify factors that predict clinical outcomes and health care needs in this population, using quantitative, administrative, and qualitative data. The aims of this proposed research are 1) to determine the two-year incidence of newly diagnosed epilepsy in the target population, 2) describe health care resource utilization of the target population using Medicare data, 3) validate the use of Medicare beneficiary data to estimate incidence of epilepsy, and 4) describe the burden of this condition in different ethnic groups.

Detailed Description

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Seniors who have had new onset seizures or newly diagnosed epilepsy will be recruited from emergency departments (EDs), neurology clinics, primary care clinics (including geriatric clinics), and other service providers from networks maintained by the Area Agencies on Aging that serve seniors in southeastern Arizona. Data will be collected in the form of bi-annual surveys,administrative data (from Medicare), in-depth interviews, and focus groups. Medicare data will be used to describe and evaluate the likelihood of being hospitalized or admitted to a long-term facility within two years of being diagnosed, medication adherence and persistence, and comparing the cost of care between the newly-diagnosed seniors with epilepsy and comparable seniors who do not have epilepsy. The feasibility and validity of using the Medicare claims data to estimate newly diagnosed epilepsy will also be assessed. Finally, the impact of epilepsy on health related quality of life, mental health, perceived stigma, and family and caregivers will also be evaluated through surveys and qualitative data collection methods, and ethnic differences will also be described.

Conditions

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Epileptic Seizures

Keywords

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seniors seizures epilepsy quality of life

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Seniors with Seizures

Seniors aged 65 or older with newly diagnosed seizures (consistent with epilepsy) or epilepsy as of October, 2010.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Aged 65 years or older
* New onset seizure or newly diagnosed epilepsy as of October 2010
* Is a resident of Pima, Cochise or Santa Cruz County

Exclusion Criteria

* Seizure dues to hyponatremia, hypoglycemia, alcohol use (with no evidence of other seizures)
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centers for Disease Control and Prevention

FED

Sponsor Role collaborator

University of Arizona

OTHER

Sponsor Role lead

Responsible Party

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Jenny Chong

Research Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Labiner, MD

Role: PRINCIPAL_INVESTIGATOR

University of Arizona

Jenny Chong, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Arizona

Locations

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Pima, Cochise, Santa Cruz Counties

Tucson, Arizona, United States

Site Status

Countries

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United States

References

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Martin R, Vogtle L, Gilliam F, Faught E. What are the concerns of older adults living with epilepsy? Epilepsy Behav. 2005 Sep;7(2):297-300. doi: 10.1016/j.yebeh.2005.05.003.

Reference Type BACKGROUND
PMID: 15996527 (View on PubMed)

Pallin DJ, Goldstein JN, Moussally JS, Pelletier AJ, Green AR, Camargo CA Jr. Seizure visits in US emergency departments: epidemiology and potential disparities in care. Int J Emerg Med. 2008 Jun;1(2):97-105. doi: 10.1007/s12245-008-0024-4. Epub 2008 Jun 5.

Reference Type BACKGROUND
PMID: 19384659 (View on PubMed)

Tallis R, Hall G, Craig I, Dean A. How common are epileptic seizures in old age? Age Ageing. 1991 Nov;20(6):442-8. doi: 10.1093/ageing/20.6.442.

Reference Type BACKGROUND
PMID: 1776595 (View on PubMed)

Other Identifiers

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10-0916-01

Identifier Type: -

Identifier Source: org_study_id