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Benefits of Post-Pyloric Feeding Tubes in Critically Ill Patients

NCT ID: NCT01343316

Last Updated: 2013-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

21 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-11-30

Study Completion Date

2013-03-31

Brief Summary

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The purpose of this study is to determine the benefit of feeding critically-ill patients beyond the stomach (post-pyloric). Furthermore, because of the advent of two new post-pyloric feeding tubes (Tiger 2 and Syncro BlueTube) designed to improve post-pyloric placement, the investigators will be evaluating the benefits of those two tubes as well.

Detailed Description

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Conditions

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Critical Illness

Keywords

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Enteral Feeds Supplemental Feeds Transpyloric Tube Nasogastric Tube

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Transgastric tube

Nasogastric (NG tube)

Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)

Intervention Type DEVICE

To determine the benefits of utilizing one type of transpyloric tube over another.

Transpyloric tube - Tiger2

Self-propelled by paristaltic waves of the stomach

Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)

Intervention Type DEVICE

To determine the benefits of utilizing one type of transpyloric tube over another.

Transpyloric tube - Syncro BlueTube

Magnetically placed

Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)

Intervention Type DEVICE

To determine the benefits of utilizing one type of transpyloric tube over another.

Interventions

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Transpyloric feeding tubes (Nasogastric Tube (NG tube), Tiger2, Syncro BlueTube)

To determine the benefits of utilizing one type of transpyloric tube over another.

Intervention Type DEVICE

Other Intervention Names

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Nasogastric Tube (NG tube) Tiger2 Syncro BlueTube

Eligibility Criteria

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Inclusion Criteria

* patients admitted to the ICU who are deemed by the attending critical care physician to warrant tube feeds and expected to receive tube feeds for more than three days
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johns Hopkins University

OTHER

Sponsor Role lead

Responsible Party

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Glenn Whitman

Associate Professor, Director of CVSICU and Adult Heart Transplant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Glenn Whitman, MD

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

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Johns Hopkins Hospital

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Montejo JC, Minambres E, Bordeje L, Mesejo A, Acosta J, Heras A, Ferre M, Fernandez-Ortega F, Vaquerizo CI, Manzanedo R. Gastric residual volume during enteral nutrition in ICU patients: the REGANE study. Intensive Care Med. 2010 Aug;36(8):1386-93. doi: 10.1007/s00134-010-1856-y. Epub 2010 Mar 16.

Reference Type BACKGROUND
PMID: 20232036 (View on PubMed)

Hsu CW, Sun SF, Lin SL, Kang SP, Chu KA, Lin CH, Huang HH. Duodenal versus gastric feeding in medical intensive care unit patients: a prospective, randomized, clinical study. Crit Care Med. 2009 Jun;37(6):1866-72. doi: 10.1097/CCM.0b013e31819ffcda.

Reference Type BACKGROUND
PMID: 19384225 (View on PubMed)

Acosta-Escribano J, Fernandez-Vivas M, Grau Carmona T, Caturla-Such J, Garcia-Martinez M, Menendez-Mainer A, Solera-Suarez M, Sanchez-Paya J. Gastric versus transpyloric feeding in severe traumatic brain injury: a prospective, randomized trial. Intensive Care Med. 2010 Sep;36(9):1532-9. doi: 10.1007/s00134-010-1908-3. Epub 2010 May 22.

Reference Type BACKGROUND
PMID: 20495781 (View on PubMed)

Heyland DK, Drover JW, MacDonald S, Novak F, Lam M. Effect of postpyloric feeding on gastroesophageal regurgitation and pulmonary microaspiration: results of a randomized controlled trial. Crit Care Med. 2001 Aug;29(8):1495-501. doi: 10.1097/00003246-200108000-00001.

Reference Type BACKGROUND
PMID: 11505114 (View on PubMed)

Davies AR, Froomes PR, French CJ, Bellomo R, Gutteridge GA, Nyulasi I, Walker R, Sewell RB. Randomized comparison of nasojejunal and nasogastric feeding in critically ill patients. Crit Care Med. 2002 Mar;30(3):586-90. doi: 10.1097/00003246-200203000-00016.

Reference Type BACKGROUND
PMID: 11990920 (View on PubMed)

Other Identifiers

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NA_00041559

Identifier Type: -

Identifier Source: org_study_id