Early Versus Delayed Treatment of Unilateral Neglect After Stroke
NCT ID: NCT01341574
Last Updated: 2021-11-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
100 participants
INTERVENTIONAL
2011-08-31
2015-12-31
Brief Summary
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One of the most promising neglect interventions is prism adaptation (PA): inducing an optical shift of the visual field by means of prism glasses. This results in a modulation of brain areas involved in neglect and in an improvement of the neglect symptoms and postural deviation.
Research questions:
1. Which period is best suited to maximize therapeutic effects? In this respect the effects of early and delayed PA will be compared, regarding neglect-, postural and cerebral measures.
2. Which factors lead to a less favorable treatment outcome or to therapy resistance for PA?
3. Will the impact of PA be larger if postural factors are taken into account in the prism therapy?
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Early phase, experimental
Neglect patients, randomized in the experimental group (Prism adaptation, optical shift of 10 degrees) in the early phase after stroke.
Prism adaptation with optical shift of 10 degrees.
Prism adaptation with optical shift of 10 degrees.
Delayed phase, experimental
Neglect patients, randomized in the experimental group (Prism adaptation, optical shift of 10 degrees) in the delayed phase after stroke.
Prism adaptation with optical shift of 10 degrees.
Prism adaptation with optical shift of 10 degrees.
Early phase, placebo
Neglect patients, randomized in the placebo group (Prism adaptation, optical shift of 0 degrees) in the early phase after stroke.
Prism adaptation optical shift of 0 degrees.
Prism adaptation with optical shift of 0 degrees.
Delayed phase, placebo
Neglect patients, randomized in the placebo group (Prism adaptation, optical shift of 0 degrees) in the delayed phase after stroke.
Prism adaptation optical shift of 0 degrees.
Prism adaptation with optical shift of 0 degrees.
Delayed phase postural, experimental
Neglect patients, randomized in the experimental group (Prism adaptation, optical shift of 10 degrees) in the delayed phase after stroke. In this group, postural aspects are taken into account.
Prism adaptation with optical shift of 10 degrees.
Prism adaptation with optical shift of 10 degrees.
Interventions
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Prism adaptation with optical shift of 10 degrees.
Prism adaptation with optical shift of 10 degrees.
Prism adaptation optical shift of 0 degrees.
Prism adaptation with optical shift of 0 degrees.
Eligibility Criteria
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Inclusion Criteria
* \> 17 years of age
* stroke patients with clinical neglect, demonstrated by neglect tests
Exclusion Criteria
* not being able to perform prism adaptation or neglect tests
18 Years
ALL
No
Sponsors
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Fund for Scientific Research, Flanders, Belgium
OTHER
University Ghent
OTHER
Responsible Party
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Principal Investigators
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Guy Vingerhoets, Ph.D., Professor
Role: PRINCIPAL_INVESTIGATOR
University Ghent
Locations
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Rehabilitation Hospital "Hof ter Schelde"
Antwerp, , Belgium
Ghent University Hospital, Center for Locomotor and Neurological Rehabilitation
Ghent, , Belgium
Ghent University Hospital, Department of Neurology
Ghent, , Belgium
Countries
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Other Identifiers
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G.0906.10
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
2011/161
Identifier Type: -
Identifier Source: org_study_id