Trial Outcomes & Findings for Evaluating Safety and Efficacy In Hepatitis C Patients After PegIntron Pen Treatment (Study P04896) (NCT NCT01340573)

NCT ID: NCT01340573

Last Updated: 2024-06-12

Results Overview

Collection of all safety reports (serious adverse events) from genotype-1 population at week-48 of treatment, from participants on pegylated interferon (PegIntron) pen plus ribavirin.

Recruitment status

TERMINATED

Target enrollment

3 participants

Primary outcome timeframe

Week-48

Results posted on

2024-06-12

Participant Flow

Participant milestones

Participant milestones
Measure
All Participants
Genotype 1 CHC Participants and Non-genotype 1 CHC partipants
Overall Study
STARTED
3
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluating Safety and Efficacy In Hepatitis C Patients After PegIntron Pen Treatment (Study P04896)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Participants
n=3 Participants
Genotype 1 CHC Participants and Non-genotype 1 CHC partipants
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
3 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex: Female, Male
Female
2 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
Region of Enrollment
Indonesia
3 participants
n=5 Participants

PRIMARY outcome

Timeframe: Week-48

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Collection of all safety reports (serious adverse events) from genotype-1 population at week-48 of treatment, from participants on pegylated interferon (PegIntron) pen plus ribavirin.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Week-24 follow-up

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Collection of all safety reports (serious adverse events) from genotype-1 population at week-24 non-treatment follow-up, from participants on pegylated interferon (PegIntron) pen plus ribavirin.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Week-24

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Collection of all safety reports (serious adverse events) from Non-genotype-1 population at week-24 of study treatment, from participants on pegylated interferon (PegIntron) pen plus ribavirin.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Week-24 follow-up

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Collection of all safety reports (serious adverse events) from Non-genotype-1 population at week-24 non-treatment follow-up, from participants on pegylated interferon (PegIntron) pen plus ribavirin.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Week-24

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Sustained virologic response (SVR) is the absence of detectable HCV RNA in serum after end of treatment.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Week-24 follow-up

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Week-48

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Week-24 follow-up

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Week 12

Population: The study was terminated early due to low enrollment. This analysis was not performed.

Participants will complete a single questionnaire during the first follow-up visit (Week 12). The questionnaire will measure the participant's satisfaction and the use of training materials for the PegIntron Pen during the course of study therapy, as measured by the participant using a 1- 5 score system provided in the questionnaire.

Outcome measures

Outcome data not reported

Adverse Events

All Participants

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Senior Vice President, Global Clinical Development

Merck Sharp & Dohme Corp.

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: OTHER