Trial Outcomes & Findings for Use of Fluticasone Propionate/Salmeterol Combination Post Emergency Department Visit (NCT NCT01332357)

NCT ID: NCT01332357

Last Updated: 2017-07-06

Results Overview

A subsequent asthma-related inpatient (IP) visit or emergency department (ED) visit were defined as visits within 6 months of the index event. The index event was defined as an asthma-related hospitalization or ED visit occuring between 2004 and 2008.

Recruitment status

COMPLETED

Target enrollment

6139 participants

Primary outcome timeframe

Data were collected during a 4-year period from January 1, 2004 to December 31, 2008.

Results posted on

2017-07-06

Participant Flow

Participants were not recruited for, nor enrolled in, this study. This study is a retrospective observational study. Data from medical records or insurance claims databases are anonymized and used to develop a cohort. All diagnoses and treatments are recorded in the course of routine medical practice.

Participant milestones

Participant milestones
Measure
Total Population
Adult and pediatric participants with persistent asthma were identified from commercially-insured and Medicaid health plan members with both medical and pharmacy benefits who had data in one of two healthcare claims databases.
Overall Study
STARTED
6139
Overall Study
COMPLETED
6139
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Use of Fluticasone Propionate/Salmeterol Combination Post Emergency Department Visit

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Total Population
n=6139 Participants
Adult and pediatric participants with persistent asthma were identified from commercially-insured and Medicaid health plan members with both medical and pharmacy benefits who had data in one of two healthcare claims databases.
Age, Continuous
22.36 Years
STANDARD_DEVIATION 17.30 • n=93 Participants
Sex: Female, Male
Female
3392 Participants
n=93 Participants
Sex: Female, Male
Male
2747 Participants
n=93 Participants
Type of Index Event
Inpatient hospitalizations
1331 visits
n=93 Participants
Type of Index Event
Emergency Department Visit
4808 visits
n=93 Participants
Charlson Comorbidity Index Scores
1.14 scores on a scale
STANDARD_DEVIATION 0.57 • n=93 Participants

PRIMARY outcome

Timeframe: Data were collected during a 4-year period from January 1, 2004 to December 31, 2008.

Population: Adult and pediatric participants with persistent asthma were identified from commercially-insured and Medicaid health plan members with both medical and pharmacy benefits who had data in one of two healthcare claims databases.

A subsequent asthma-related inpatient (IP) visit or emergency department (ED) visit were defined as visits within 6 months of the index event. The index event was defined as an asthma-related hospitalization or ED visit occuring between 2004 and 2008.

Outcome measures

Outcome measures
Measure
Total Population
n=6139 Participants
Adult and pediatric participants with persistent asthma were identified from commercially-insured and Medicaid health plan members with both medical and pharmacy benefits who had data in one of two healthcare claims databases.
Number of Participants With an Asthma-related Event Occurring Between 1 and 6 Months Following the Index Event
915 participants

Adverse Events

Total Population

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

GSK Response Center

GlaxoSmithKline

Phone: 866-435-7343

Results disclosure agreements

  • Principal investigator is a sponsor employee GSK agreements may vary with individual investigators, but will not prohibit any investigator from publishing. GSK supports the publication of results from all centers of a multi-center trial but requests that reports based on single-site data not precede the primary publication of the entire clinical trial.
  • Publication restrictions are in place

Restriction type: OTHER