An Bioequivalence Study Of Xanax Extended Release Tablets From Two Different Manufacturing Sites

NCT ID: NCT01330472

Last Updated: 2021-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2011-06-30

Brief Summary

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Study to evaluate if Xanax sustained release tablets manufactured at two different sites provide similar drug levels in the blood.

Detailed Description

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Conditions

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Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Xanax XR tablets 3 mg (sourced from Caugus)

Xanax XR tablets 3 mg (sourced from Caugus), 1 x 3 mg (REFERENCE)

Group Type ACTIVE_COMPARATOR

Xanax XR tablets 3 mg (sourced from Caugus)

Intervention Type DRUG

Tablets, 3 mg, single dose

Xanax XR tablets 3 mg (sourced from Barceloneta),

Xanax XR tablets 3 mg (sourced from Barceloneta), 1 x 3 mg (TEST)

Group Type EXPERIMENTAL

Xanax XR tablets 3 mg (sourced from Barceloneta)

Intervention Type DRUG

Tablets, 3 mg, single dose

Interventions

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Xanax XR tablets 3 mg (sourced from Caugus)

Tablets, 3 mg, single dose

Intervention Type DRUG

Xanax XR tablets 3 mg (sourced from Barceloneta)

Tablets, 3 mg, single dose

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy male and/or female subjects between the ages of 20 and 55 years, inclusive.
* An informed consent document signed and dated by the subject.

Exclusion Criteria

* Evidence or history of clinically significant abnormality.
* A positive urine drug screen.
* Subjects who are hypersensitive to alprazolam or related compounds.
Minimum Eligible Age

20 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Pfizer Investigational Site

Singapore, , Singapore

Site Status

Countries

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Singapore

Related Links

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Other Identifiers

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A6131025

Identifier Type: -

Identifier Source: org_study_id

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