TRIGEN SURESHOT™ Distal Targeting System Study

NCT ID: NCT01327508

Last Updated: 2018-03-14

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2013-06-30

Brief Summary

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The objective of this study is to quantitate the amount of radiation both subjects and surgeons are exposed to during intramedullary nailing of the femur using the TRIGEN SURESHOT Distal Targeting System versus Standard nailing instrumentation.

Detailed Description

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The TRIGEN SURESHOT™ Distal Targeting System was designed to be an intraoperative image-guided localization system to aid with drill positioning for screws during intramedullary nailing distal interlocking. It is hypothesized that this system will aid in identification of the distal holes leading to reduced exposure to radiation. The SURESHOT System provides information to the surgeon that is used to place surgical instruments utilizing electromagnetic tracking data obtained intraoperatively. It is indicated for long bone fractures treated with intramedullary nailing in which the use of stereotactic surgery may be appropriate. The hypothesis is that using the TRIGEN SURESHOT™ Distal Targeting System will allow accurate distal locking while effectively decreasing the amount of radiation exposure compared to the standard instrumentation process.

Conditions

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Femoral Shaft Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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TRIGEN SURESHOT Distal Targeting

TRIGEN SURESHOT Distal Targeting Instrumentation is utilized to find screw holes.

Group Type EXPERIMENTAL

TRIGEN SURESHOT Distal Targeting Instrumentation.

Intervention Type DEVICE

image-guided localization system

Standard Nailing Instrumentation.

Free-hand technique utilizes x-rays to find screw holes

Group Type ACTIVE_COMPARATOR

Free-hand technique

Intervention Type OTHER

Free-hand technique utilizes x-rays to find screw holes.

Interventions

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TRIGEN SURESHOT Distal Targeting Instrumentation.

image-guided localization system

Intervention Type DEVICE

Free-hand technique

Free-hand technique utilizes x-rays to find screw holes.

Intervention Type OTHER

Other Intervention Names

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SURESHOT

Eligibility Criteria

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Inclusion Criteria

* Unilateral femoral shaft fracture requiring intramedullary nailing in which the use of stereotactic surgery may be appropriate.
* Subject is between 18-80 years of age.
* Subject is skeletally mature
* Subject is of legal age and capable of providing legal consent.
* Subject is suitable for current Intramedullary Nailing procedure
* Subject willing to accept randomization either to the TRIGEN SURESHOT Distal Targeting System or TRIGEN standard instrumentation.

Exclusion Criteria

* Femur shaft fracture not amenable to intramedullary nailing in which the use of sterotactic surgery may be inappropriate.
* Fracture with vascular injury (Gustilo Type IIIC) requiring repair
* Open fractures where open wound is in communication with distal targeting holes and therefore would influence duration of locking procedure (i.e. potentially no need for incisions for locking screw placement).
* Fracture of the Metaphyseal distal femur with intraarticular comminution
* Known Pathological Fracture
* Subject is a prisoner
* Operative procedure for closed fracture is scheduled for greater than 2 weeks for closed fractures
* Subject has cognitive issue/mental status conditions that preclude intramedullary nailing in the judgment of the investigator.
* Contralateral femoral shaft fracture
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Smith & Nephew, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Samir Mehta, M.D.

Role: PRINCIPAL_INVESTIGATOR

Orthopaedic Surgery, Hospital of the University of Pennsylvania

Animesh Agarwal, M.D.

Role: PRINCIPAL_INVESTIGATOR

UT Health Science Center, Dept of Orthopaedic

Marcus Sciadini, M.D

Role: PRINCIPAL_INVESTIGATOR

University of Maryland Baltimore, Department of Orthopaedics

Steven Olson, M.D.

Role: PRINCIPAL_INVESTIGATOR

Duke University Medical Center of Orthopaedic

Chad Coles, M.D.

Role: PRINCIPAL_INVESTIGATOR

Nova Scotia Health Authority

Richard Vlasak, M.D.

Role: PRINCIPAL_INVESTIGATOR

Dept. of Orthopaedics & Rehab University of Florida

Locations

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UC Davis Medical Center

Sacramento, California, United States

Site Status

Department of Orthopaedics and Rehabilitation

Gainesville, Florida, United States

Site Status

University of Maryland Medical Center

Baltimore, Maryland, United States

Site Status

Duke University Medical Center

Durham, North Carolina, United States

Site Status

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

University Hospital Trauma Service

San Antonio, Texas, United States

Site Status

Capital District Health Authority

Halifax, Nova Scotia, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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09-TRI-01

Identifier Type: -

Identifier Source: org_study_id

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