Natural History of Mineral Metabolism Parameters and Protein-bound Toxins in Incident Peritoneal Dialysis Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

96 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-07-31

Study Completion Date

2017-01-31

Brief Summary

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The aims of this study are

1. To evaluate the natural history of plasma concentrations and renal and peritoneal clearances of small water-soluble uremic retention molecules (URM), 'middle molecules', and protein bound URM in incident peritoneal dialysis (PD) patients.
2. To evaluate the natural history and determinants of the generation rate of URM originating from bacterial protein fermentation in PD patients.
3. To evaluate the natural history of biochemical parameters of mineral metabolism in incident PD patients.

Detailed Description

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Conditions

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Complication of Peritoneal Dialysis

Keywords

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biochemical parameters mineral metabolism protein-bound uremic retention solutes incident PD patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Incident PD patients, defined as patients who started on PD as first renal replacement therapy less than 8 weeks before inclusion
* written informed consent
* age \> 18 years old

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Björn Meijers

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pieter Evenepoel, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Leuven, Belgium

Locations

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University Hospital

Leuven, Vlaams-Brabant, Belgium

Site Status

Countries

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Belgium

Other Identifiers

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FWO01-03-21

Identifier Type: -

Identifier Source: org_study_id