Investigation of Safety and Efficacy of SB Injection in Patients With Advanced and Metastatic Non-small Cell Lung Cancer

NCT ID: NCT01305967

Last Updated: 2011-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-01-31

Study Completion Date

2011-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine efficacy of SB injection in Non Small Cell Lung Cancer.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

All eligible patients will receive SB injection therapy for 4 cycles (14\~21 days for each cycle). SB injection treatment could be continue after completion of therapy cycles until 6th cycle. It depends on the investigator's decision and patient's will. Efficacy will be evaluated every two cycles.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Non Small Cell Lung Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

SB injection

Infusion SBinjection of 21.87ml/m\^2, Intravenous route, 16times for 2.5 months

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age of 18-70 years
* Patients with histologically or cytologically confirmed Non-Small Cell Lung Cancer
* Patients who had failed more than 1 cycle of standard therapy with advanced or metasatic stage not available to any of resectable surgery or radiotherapy.
* Patients with measurable lesions
* Eatern Cooperative Oncolgy Group status 0 to 2.
* Life expectancy \>/= 5 months
* Patients with adequate organ(heart, kidney, liver)and bone marrow function, as defined by

1. Absolute neutrophil count \>/= 1.5 x 10\^9/L, Platelet count \>/= 100 x 10\^9/L
2. Total bilirubin \</= upper limit of normal
3. Aspartate Aminotransferase and/or Alanine Aminotransferase \</= 2 x upeer limit of normal
4. creatinine \</= 1.5 x upeer limit of normal
* Patients who have signed the informed consent form.

Exclusion Criteria

* Female volunteers admitted to the study must be using a reliable means of contraception
* Received radiation therapy within 6 weeks before randomization
* Known brain or spinal cord metastases
* Have acute infection
* Have active infection or serious concomitant systemic disorder incompatible with the study
* Presence or history of malignancy other than Non-Small Cell Lung Cancer
* Have severe neurologic or psychological disorder
* Patients who have to receive other chemo-radiotherapy or immunotherapy
* Patients who have received chemotherapy within the previous 30 days
* Patients who are candidates for combined modality treatment.
* Patients who have participated in a clinical study within the previous 30 days
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

SBPharmaceutical IND, Co., LTD

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

SBPharmaceutical IND, Co., LTD

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jae-yong Park, Professor

Role: PRINCIPAL_INVESTIGATOR

Kyungpook University Hospital

Seung-beom Han, Professor

Role: PRINCIPAL_INVESTIGATOR

Keimyung University Dongsan Medical Center

Chae-young Lee, Medical Doctor

Role: PRINCIPAL_INVESTIGATOR

Anyang Sam Medical Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Keimyung University Dongsan Hospital

Daegu, Jung-gu, South Korea

Site Status COMPLETED

Kyungpook University Hospital

Deagu, Jung-gu, South Korea

Site Status COMPLETED

Sam Anyang Medical Center

Anyang, Man-an-gu, South Korea

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

South Korea

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Chae-young Lee, Medical Doctor

Role: CONTACT

031-467-9188

A-young Shin, Registered Nurse

Role: CONTACT

031-467-9767

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Cae-young Lee, MD

Role: primary

031-467-9188

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SB Injection

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.