BLI801 Laxative in Constipated Adults

NCT ID: NCT01301781

Last Updated: 2012-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Brief Summary

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A pilot study to evaluate the safety and efficacy of BLI801 vs. placebo in constipated adults.

Detailed Description

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Conditions

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Constipation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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BLI801 laxative

BLI801 laxative - oral solution

Group Type EXPERIMENTAL

BLI801

Intervention Type DRUG

BLI801 laxative - oral solution

Placebo

BLI801 placebo - oral solution

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

BLI801 placebo - oral solution

Interventions

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BLI801

BLI801 laxative - oral solution

Intervention Type DRUG

Placebo

BLI801 placebo - oral solution

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Constipated, defined by ROME III definition
* Subject has \< 3 satisfactory BMs during the run-in period

Exclusion Criteria

* Subjects with known or suspected ileus, gastrointestinal obstruction, gastric retention, bowel perforation, toxic colitis, toxic megacolon
* Subjects taking laxatives or prokinetic agents that refuse to discontinue these treatments.
* Subjects who are allergic to any BLI801 component
* Subjects taking narcotic analgesics or other medications known to cause constipation.
* Subjects who, in the opinion of the Investigator, should not be included in the study for any reason, including inability to follow study procedures
* Subjects who have participated in an investigational clinical, surgical, drug, or device study within the past 30 days
* Subjects with an active history of drug or alcohol abuse
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Braintree Laboratories

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Advanced Clinical Research Institute

Anaheim, California, United States

Site Status

Jupiter Research

Jupiter, Florida, United States

Site Status

United Medical Research

New Smyrna Beach, Florida, United States

Site Status

Long Island GI Research Group

Great Neck, New York, United States

Site Status

Countries

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United States

Other Identifiers

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BLI801-201

Identifier Type: -

Identifier Source: org_study_id