Liraglutide as Additional Treatment in Patients With Type 1 Diabetes Mellitus

NCT ID: NCT01299012

Last Updated: 2017-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-10-31

Study Completion Date

2013-06-30

Brief Summary

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Evaluating the use of Liraglutide in patients with Type 1 Diabetes.

Detailed Description

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This investigation will be a retrospective chart review of in type 1 diabetics who have been treated with liraglutide. The study will be conducted at Diabetes-Endocrinology Center of WNY at Millard Fillmore Hospital, affiliated to the State University of New York at Buffalo.

Study Population: 40 patients with type 1 diabetes on treatment with either continuous subcutaneous insulin infusion (CSII; also known as insulin pump) or multiple (four or more) injections of insulin per day on continuous glucose monitoring system (CGMS) will be included in the study. These patients with type 1 diabetes have been treated with liraglutide in addition to insulin. The investigators would retrospectively review their charts to evaluate decreases in fasting, postprandial and the overall mean glucose concentrations.

The investigators will compare the mean fasting, the mean weekly glucose and the standard deviation of weekly blood glucose concentrations as recorded by continuous glucose monitoring prior to and following one week and 12 weeks of treatment with liraglutide daily. In addition, the investigators will compare the time spent at glucose concentrations \>150 and 200mg/dl and \<70 and \<40 mg/dl. HbA1c levels before and after 12 weeks of treatment with liraglutide daily will be compared.

Conditions

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Type 1 Diabetes Mellitus

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Interventions

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Liraglutide

Liraglutide s/c 0.6mg once daily.

Intervention Type DRUG

Other Intervention Names

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Victoza

Eligibility Criteria

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Inclusion Criteria

* Type 1 Diabetes Mellitus

Exclusion Criteria

* Type 2 Diabetes Mellitus
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University at Buffalo

OTHER

Sponsor Role lead

Responsible Party

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Paresh Dandona

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Paresh Dandona

Role: PRINCIPAL_INVESTIGATOR

University at Buffalo

Other Identifiers

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1954

Identifier Type: -

Identifier Source: org_study_id

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