Evaluation of a New Catheter Material for Intermittent Catheterization

NCT ID: NCT01295281

Last Updated: 2021-11-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

107 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2011-05-31

Brief Summary

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The hypothesis to be investigated is if the tolerability of intermittent catheterization with Polyolefin Based Elastomer (POBE) 2.0 and Polyvinyl Chloride (PVC) is clinically equal - i.e. clinically non-inferior when using POBE 2.0 compared to PVC.

Secondary objectives are to evaluate the safety and the subject's perception associated with the use of the catheters, assessed by the recording of adverse events and the ease of handling by means of a subjective assessment scale.

Detailed Description

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Conditions

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Catheterization (Clean, Intermittent Urinary Catheterization)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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LoFric POBE 2.0 - PVC

First period (7 days) use of LoFric POBE 2.0 followed by second period (7 days) use of LoFric PVC

Group Type EXPERIMENTAL

LoFric POBE 2.0

Intervention Type DEVICE

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

LoFric PVC

Intervention Type DEVICE

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

LoFric PVC - POBE 2.0

First period (7 days) use of LoFric PVC followed by second period (7 days) use of LoFric POBE 2.0.

Group Type EXPERIMENTAL

LoFric POBE 2.0

Intervention Type DEVICE

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

LoFric PVC

Intervention Type DEVICE

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

Interventions

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LoFric POBE 2.0

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

Intervention Type DEVICE

LoFric PVC

To be used at least twice daily, during 7 days. Treatment period 1 and 2 last 7 days, respectively.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Provision of informed consent
* Males, aged 18 years and over
* Maintained urethra sensibility
* Practice intermittent self-catheterization at least 2 times daily
* Using catheters in the length of 40 cm and size charrière (Ch) 12 or Ch 14
* Experienced practitioners of intermittent self-catheterization defined as a minimum of three months on therapy
* Experience of using LoFric catheter within the last 12 months prior to study entry
* Adults able to read, write and understand information given to them regarding the study

Exclusion Criteria

* Ongoing, symptomatic urinary tract infection (UTI) at enrolment as judged by investigator
* Known urethral stricture at enrolment as judged by investigator
* Involvement in the planning and/or conduct of the study (applies to both Astra Tech staff or staff at the study site)
* Previous enrolment or randomisation of treatment in the present study
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Wellspect HealthCare

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Birgit Johansson, Urotherapist

Role: PRINCIPAL_INVESTIGATOR

Kärnsjukhuset Skövde

Locations

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Kirurg och Urologmottagningen, Alingsås lasarett

Alingsås, , Sweden

Site Status

Urologcentrum

Borås, , Sweden

Site Status

Kirurg- och urologmottagningen, Gävle Sjukhus

Gävle, , Sweden

Site Status

Urologmottagningen, Lundby Sjukhus

Gothenburg, , Sweden

Site Status

Uroterapimottagningen Kärnsjukhuset Skövde

Skövde, , Sweden

Site Status

Urologmottagningen Uddevalla sjukhus

Uddevalla, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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LOF-0018

Identifier Type: -

Identifier Source: org_study_id