Survey of Osteoarthritis Real World Therapies (MK-0663-140)

NCT ID: NCT01294696

Last Updated: 2024-08-29

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 1261 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-10-31
• Study Completion Date: 2013-01-31

Brief Summary

This was a study to estimate the proportion of participants with osteoarthritis of the knee(s) who were treated with oral or topical analgesics for their symptoms, who did and did not report adequate pain relief at Baseline and to characterize their pain level over a 12-month follow-up period.

Conditions

Osteoarthritis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

All Enrolled Participants

All participants will be treated according to standard medical guidelines or usual clinical practice standards of the investigating physician.

Standard of care for treatment of osteoarthritis (OA) of knee(s)

Intervention Type: DRUG

All participants will be treated according to standard medical guidelines or usual clinical practice standards of the investigating physician.

Interventions

Standard of care for treatment of osteoarthritis (OA) of knee(s)

All participants will be treated according to standard medical guidelines or usual clinical practice standards of the investigating physician.

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Clinical diagnosis of primary osteoarthritis of the knee(s)
• Presently receiving prescribed oral or topical analgesics for a minimum duration of two weeks prior to enrollment

Exclusion Criteria

• Arthritis other than primary osteoarthritis
• Treatment with disease-modifying antirheumatic drugs (DMARDS), methotrexate or biologics
• Subtotal or total joint replacement in the affected knee
• Chronic severe pain of other causes that in the opinion of the investigator may require long-term analgesia or confound the present study
• Currently enrolled in a clinical trial or who have participated in a clinical trial within the past 30 days

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Organon and Co

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

References

Conaghan PG, Peloso PM, Everett SV, Rajagopalan S, Black CM, Mavros P, Arden NK, Phillips CJ, Rannou F, van de Laar MA, Moore RA, Taylor SD. Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies. Rheumatology (Oxford). 2015 Feb;54(2):270-7. doi: 10.1093/rheumatology/keu332. Epub 2014 Aug 23.

Reference Type: RESULT

PMID: 25150513 (View on PubMed)

Other Identifiers

0663-140

Identifier Type: -

Identifier Source: org_study_id