Local Triamcinolone Injection in Active Thyroid Orbitopathy

NCT ID: NCT01280214

Last Updated: 2011-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-02-28

Study Completion Date

2013-02-28

Brief Summary

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Comparing the effectiveness of subconjunctival and peribulbar Triamcinolone injection to systemic Steroid therapy for patients with active thyroid orbitopathy.

Detailed Description

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Local Steroid treatment may help in active thyroid orbitopathy. till today, systemic Steroids are the treatment for active thyroid orbitopathy which is associated with systemic adverse effects.

In this study the investigators want to compare the effectiveness of local Triamcinolone therapy for active thyroid orbitopathy.

Conditions

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Thyroid Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Triamcinolone

Group Type EXPERIMENTAL

Triamcinolone

Intervention Type DRUG

Subconjunctival and peribulbar, 40 mg/ml, 3 monthly injection

Interventions

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Triamcinolone

Subconjunctival and peribulbar, 40 mg/ml, 3 monthly injection

Intervention Type DRUG

Other Intervention Names

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kenalog

Eligibility Criteria

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Inclusion Criteria

* Age\>18 years.
* Active thyroid orbitopathy according to clinical activity score\>=3.

Exclusion Criteria

* Intraorbital or active infections.
* Tuberculosis.
* Other orbital disease.
* Pregnancy.
* Compressive optic neuropathy.
* Systemic steroid therapy within 6 months of study start.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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HaEmek Medical Center, Israel

OTHER

Sponsor Role lead

Responsible Party

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Haemek Medical center

Principal Investigators

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Daniel Briscoe, MD

Role: STUDY_CHAIR

haemek medical center

Central Contacts

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Daniel Briscoe, MD

Role: CONTACT

972-4-6494344

Other Identifiers

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EMC119710ctil

Identifier Type: -

Identifier Source: org_study_id

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