Study of PTPN22 C1858T Polymorphism in Children and Adolescents of Greek Origin With T1DM
NCT ID: NCT01276743
Last Updated: 2014-02-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
200 participants
OBSERVATIONAL
2010-02-28
2013-02-28
Brief Summary
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In this observational case-control study, we aimed at confirming the role of PTPN22, C1858T polymorphism in T1DM predisposition in a Greek population.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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T1DM
Children and adolescents with T1DM
No interventions assigned to this group
Unaffected Population
Population not known to be affected by T1DM
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Diagnosis of T1DM according to American Diabetes Association (ADA) Criteria as well as according to International Society for Pediatric and Adolescent Diabetes (ISPAD) Guidelines
* Unrelated male and female subjects
* 1-20 years of age
* Come from Greece (At least 3 grandparents are Greek)
* At least one year post onset of T1DM
* Sign written informed consent
For the controls
* Unrelated nondiabetic male and female subjects with no family history of T1DM
* Equal to or greater than 18 years of age
* Come from Greece (At least 3 grandparents are Greek)
* Be screened by a questionnaire to ensure the absence of any diagnostic evidence of autoimmune diseases or family history (first- or second-degree relatives) of T1DM
* Sign written informed consent
Exclusion Criteria
For the controls
•Subjects who do not meet the criteria above
3 Years
18 Years
ALL
Yes
Sponsors
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Aristotle University Of Thessaloniki
OTHER
Responsible Party
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Styliani Giza
MD, MSc, PhD, 4th Department of Pediatrics, Faculty of Medicine, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece
Principal Investigators
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Assimina Galli-Tsinopoulou, MD, PhD
Role: STUDY_CHAIR
Aristotle University Of Thessaloniki
Locations
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Unit of Pediatric Endocrinology, Diabetes and Metabolism, 4th Department of Pediatrics, Medical School, Aristotle University of Thessaloniki
Thessaloniki, , Greece
Countries
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Other Identifiers
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01051979
Identifier Type: -
Identifier Source: org_study_id
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