Use of an Ocular Telemetry Sensor in Tafluprost Treated Patients

NCT ID: NCT01263535

Last Updated: 2012-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2012-05-31

Brief Summary

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This clinical trial is designed to investigate the performance of SENSIMED Triggerfish® during 24-hour continuous IOP fluctuation monitoring, defined as the number of valid recording intervals over the 24-hour period.

The investigation will recruit male and female patients older than 18 years and diagnosed with glaucoma and treated with tafluprost in both eyes. 20 subjects will be enrolled in the study. Patients will be considered enrolled in the study upon signature of informed consent. A screening visit and one 24-hour IOP fluctuation monitoring session during a 36-hour hospitalisation, are planned for each patient.

Detailed Description

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Conditions

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Glaucoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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SENSIMED Triggerfish

Group Type EXPERIMENTAL

SENSIMED Triggerfish

Intervention Type DEVICE

Contact lens-based device for the continuous recording of IOP fluctuations, with a portable recording system

Interventions

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SENSIMED Triggerfish

Contact lens-based device for the continuous recording of IOP fluctuations, with a portable recording system

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Older than 18 years.
* Untreated IOP of ≥22 mmHg in both eyes.
* Documented, typical glaucomatous visual field (VF) loss (nasal step, or arcuate, paracentral or Seidel's scotoma) determined by automated static threshold perimetry (Octopus 100), and glaucomatous optic nerve head cupping (neural rim notching or saucerization) in both eyes.
* Patients under tafluprost treatment since at least 4 weeks in both eyes.
* Patients who accept signing an informed consent approved by the Ethics Committee.

Exclusion Criteria

* Patients not able to understand the nature of the research
* Patients under tutorship
* Corneal abnormalities in both eyes
* Subjects with contraindications for wearing contact lenses
* History of ocular surgery within the last 3 months
* Known hypersensitivity to tafluprost or to any of its excipients
* Full-frame metal glasses during monitoring with SENSIMED Triggerfish®
* Pregnancy and lactation
* Simultaneous participation in other clinical research
* Patients with evidence of ocular infection or inflammation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Geneva

OTHER

Sponsor Role collaborator

Sensimed AG

INDUSTRY

Sponsor Role lead

Responsible Party

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University Hospital Geneva

Locations

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University Hospital Geneva

Geneva, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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09/06

Identifier Type: -

Identifier Source: org_study_id