The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

NCT ID: NCT01255267

Last Updated: 2010-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Study Classification

OBSERVATIONAL

Brief Summary

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In this study, we evaluate the acute coronary syndrome patients to see if there is correlation between platelet activity, genetic polymorphism (CYP2C19 and ABCB1), serum adipokines level, and Clopidogrel responsiveness.

Detailed Description

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Conditions

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Acute Coronary Syndrome Chronic Coronary Artery Disease

Keywords

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Acute coronary syndrome and chronic coronary artery disease patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Acute coronary syndrome patients

No interventions assigned to this group

Chronic coronary artery disease patients

No interventions assigned to this group

Healthy control

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age \> 18 y/o
2. Acute coronary syndrome patients
3. Chronic coronary artery disease patients
4. Healthy volunteers

Exclusion Criteria

1. Patient refusal
2. Allergy to Clopidogrel
3. Receive Gp IIb/IIIa inhibitor simultaneously
4. Cancer history
5. Severe renal and liver function impairment
6. Coagulopathy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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China Medical University Hospital

OTHER

Sponsor Role lead

Locations

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China Medical University Hospital

Taichung, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yu-Chen Wang, MD

Role: CONTACT

Phone: 886-4-22052121

Email: [email protected]

Facility Contacts

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Yu-Chen Wang, MD

Role: primary

Other Identifiers

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DMR99-IRB-041

Identifier Type: -

Identifier Source: org_study_id