Prevalence of Creatinine Phosphokinase Increase in Patients With Solid Tumors Treated by Inhibitors of Tyrosine Kinases

NCT ID: NCT01248429

Last Updated: 2012-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

154 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-11-30

Study Completion Date

2011-02-28

Brief Summary

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This study describes the elevation of CPK in patient treated for solid tumors by TKI

Detailed Description

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Conditions

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Cancer Solid Tumor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient treated by TKI

Any patient with solid tumor and treated by Thyrosine Kinase Inhibitor for at least 1 week

CPK dosage

Intervention Type BIOLOGICAL

CPK dosage during a blood sample realized at least one week after the begining of the treatment

Clinical exam

Intervention Type OTHER

Examination of the patient for myalgia, cramps, medical history and concomitant medication

Interventions

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CPK dosage

CPK dosage during a blood sample realized at least one week after the begining of the treatment

Intervention Type BIOLOGICAL

Clinical exam

Examination of the patient for myalgia, cramps, medical history and concomitant medication

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with solid tumor treated by inhibitor of tyrosin kinase for at least 1 week
* Patient examined AND with a routine blood test planned
* Patient informed of procedure for the study who was not opposed to it

Exclusion Criteria

* Patient treated for malignant hemopathy
* Patient no treated by inhibitor of thyrosine kinase or for less than 1 week
* Patients with no routine blood laboratory tests planned
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Oscar Lambret

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Antoine ADENIS, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Oscar Lambret

Locations

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Centre Paul Papin

Angers, , France

Site Status

Hôpital Jean Minjoz

Besançon, , France

Site Status

CHU Bordeaux

Bordeaux, , France

Site Status

Institut Bergonié

Bordeaux, , France

Site Status

Centre François Baclesse

Caen, , France

Site Status

Centre Jean Perrin

Clermont-Ferrand, , France

Site Status

Hôpital Henri Mondor - APHP

Créteil, , France

Site Status

Centre Oscar Lambret

Lille, , France

Site Status

CHU Limoges

Limoges, , France

Site Status

Hôpital Edouard Herriot

Lyon, , France

Site Status

Centre Léon Bérard

Lyon, , France

Site Status

Institut Paoli Calmettes

Marseille, , France

Site Status

Centre Val d'Aurelle

Montpellier, , France

Site Status

Centre Antoine Lacassagne

Nice, , France

Site Status

Hôpital Saint-Louis - APHP

Paris, , France

Site Status

Hôpital Cochin - APHP

Paris, , France

Site Status

Hôpital Tenon - APHP

Paris, , France

Site Status

Institut Curie

Paris, , France

Site Status

Institut Jean Godinot

Reims, , France

Site Status

CHU Robert Debré

Reims, , France

Site Status

Centre Eugène Marquis

Rennes, , France

Site Status

Centre Henri Becquerel

Rouen, , France

Site Status

Centre René Huguenin

Saint-Cloud, , France

Site Status

Institut de Cancérologie de la Loire

Saint-Priest-en-Jarez, , France

Site Status

Institut Claudius Régaud

Toulouse, , France

Site Status

Centre Alexis Vautrin

Vandœuvre-lès-Nancy, , France

Site Status

Institut Gustave Roussy

Villejuif, , France

Site Status

Countries

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France

Other Identifiers

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TKI-CPK 1003

Identifier Type: -

Identifier Source: org_study_id

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