A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction

NCT ID: NCT01248325

Last Updated: 2010-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2011-07-31

Brief Summary

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Sixty subjects will take part in this study. The subjects will be randomly assigned in a 1:1 ratio between the two arms of study. (Group A: Solution of Luffa Nasal Operculate 5mg/mL, Group B: saline).

The subjects will use the study medication or comparative, according to their randomization, for a treatment period of 3 to 7 days. A follow-up visit will be made 15 days after initiation of treatment.

Detailed Description

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Conditions

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Rhinitis Sinusitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Luffa Operculate Nasal Solution 5mg/mL

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Group Type EXPERIMENTAL

Luffa Operculate Nasal Solution 5mg/mL

Intervention Type DRUG

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Saline Solution (NaCl 0,9%)

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Group Type ACTIVE_COMPARATOR

Saline Solution (NaCl 0,9%)

Intervention Type DRUG

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Interventions

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Luffa Operculate Nasal Solution 5mg/mL

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Intervention Type DRUG

Saline Solution (NaCl 0,9%)

The treatment will start on the first visit in which subjects will be instructed to instill in the nasal passages, 3 drops of the product by morning and 3 drops of the product at night.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Subjects of both sexes aged over 18 years.
* Presence of nasal congestion due to colds, rhinitis, influenza, sinusitis and acute or chronic sinusitis
* Sign the Informed Consent Form
* Comply the study requirements and attend to study visits
* Female subjects must have a NEGATIVE urine pregnancy test during the screening.

Exclusion Criteria

* Known allergy to any study product component
* Subject pregnant, lactating or of childbearing potential and not using adequate and effective contraceptive
* Vasoconstrictor nasal topic or oral
* Use of a decongestant nasal whatever the route of administration
* Use of intranasal corticosteroids
* Use of antiallergic
* Use of medication containing atropine
* Subjects that are participating in another study or who participated in another study, less than 12 months
* Any subjects deemed unsuitable for study by the Principal Investigator
* Abuse of alcohol or illicit drugs
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zurita Laboratorio Farmaceutico Ltda.

INDUSTRY

Sponsor Role lead

Responsible Party

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Zurita Laboratório Farmacêutico Ltda

Principal Investigators

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Luis Gregório, doctor's

Role: PRINCIPAL_INVESTIGATOR

Universidade Federal de São Paulo/Hospital São Paulo/Escola Paulista de Medicina/UNIFESP

Locations

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Universidade Federal de São Paulo/Hospital São Paulo/Escola Paulista de Medicina/UNIFESP

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

Central Contacts

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Andréa Martinez, doctor's

Role: CONTACT

Phone: (11 55) 5082-3634

Email: [email protected]

Other Identifiers

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ZUR-LO-2009

Identifier Type: -

Identifier Source: org_study_id