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Sensory Attention Focused Exercise in Parkinson's Disease

NCT ID: NCT01246700

Last Updated: 2010-11-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

76 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-06-30

Study Completion Date

2010-12-31

Brief Summary

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The purpose of this study is 1.) to determine if sensory attention focused exercise is an effective management strategy for Parkinson's disease, and 2.) to identify if the benefits are a result of strength gains.

Detailed Description

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Currently, there is no cure for Parkinson's disease (PD) and although medication offers symptom reduction, there are many negative side effects associated with medication use. Thus, there has been an increased emphasis on exercise interventions for symptom reduction. Recent research has shown that both sensory attention focused exercise (SAFEx) and strength training interventions improved disease severity more so than other exercise interventions (such as aerobic, aquatic and no exercise). Upon closer examination, SAFEx showed further symptom improvements than the strength training program. Thus exists the need to further examine SAFEx using a standardized protocol - a single-blind randomized double-crossover trial - that has been used sparingly in exercise interventions. In addition, the 30-second chair stand has been implemented into the testing protocol, as it has been shown to be a reliable measurement of functional strength for older adults. This test was implemented in order to identify the functional strength gains, if any, that are associated with SAFEx. It is hypothesized that the SAFEx intervention will improve disease symptoms in PD, and that the results will not be due to strength gains.

Conditions

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Parkinson's Disease

Keywords

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Parkinson's disease Randomized single-blind crossover trial Sensory Attention Focused Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Group A

Participants received 12 weeks of Sensory Attention Focused Exercise, then received 12 weeks of no exercise.

Group Type EXPERIMENTAL

Sensory Attention Focused Exercise (SAFEx)

Intervention Type OTHER

Consisted of 12 weeks for SAFEx intervention, 3 times a week for an hour each session. Participants complete dynamic balance activities and a variety of seated stretches and range of motion activities. Participants are cued to focus on sensation and proprioception of limbs.

Group A received SAFEx for 12 weeks then received no treatment for 12 weeks.

Group B

Participants received no treatment for 12 weeks, then received Sensory Attention Focused Exercise for 12 weeks.

Group Type EXPERIMENTAL

Sensory Attention Focused Exercise (SAFEx)

Intervention Type OTHER

Consisted of 12 weeks for SAFEx intervention, 3 times a week for an hour each session. Participants complete dynamic balance activities and a variety of seated stretches and range of motion activities. Participants are cued to focus on sensation and proprioception of limbs.

Group B received no treatment for 12 weeks, then received SAFEx for 12 weeks.

Interventions

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Sensory Attention Focused Exercise (SAFEx)

Consisted of 12 weeks for SAFEx intervention, 3 times a week for an hour each session. Participants complete dynamic balance activities and a variety of seated stretches and range of motion activities. Participants are cued to focus on sensation and proprioception of limbs.

Group A received SAFEx for 12 weeks then received no treatment for 12 weeks.

Intervention Type OTHER

Sensory Attention Focused Exercise (SAFEx)

Consisted of 12 weeks for SAFEx intervention, 3 times a week for an hour each session. Participants complete dynamic balance activities and a variety of seated stretches and range of motion activities. Participants are cued to focus on sensation and proprioception of limbs.

Group B received no treatment for 12 weeks, then received SAFEx for 12 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnosis of PD by a clinician/neurologist
* absence of mentation
* established medication schedule and dosage

Exclusion Criteria

* mentation
* change in medication during period of study
* change in exercise level during period of study
* inability to complete the exercise program
* absence of 5 or more classes, or absence of 3 or more classes in sequence
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Canada, Young Men's Christian Association (YMCA)

UNKNOWN

Sponsor Role collaborator

Parkinson Society Canada

OTHER

Sponsor Role collaborator

Canada, Sun Life Financial

UNKNOWN

Sponsor Role collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

Sun Life Financial Movement Disorders Research and Rehabilitation Centre

OTHER

Sponsor Role lead

Responsible Party

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Sun Life Financial Movement Disorders Research and Rehabilitation Centre; Wilfrid Laurier University

Principal Investigators

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Quincy J Almeida, Ph.D

Role: STUDY_DIRECTOR

Sun Life Financial Movement Disorders Research and Rehabilitation Centre

Locations

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Sun Life Financial Movement Disorders Research and Rehabilitation Centre

Waterloo, Ontario, Canada

Site Status

Countries

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Canada

References

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Sage MD, Almeida QJ. Symptom and gait changes after sensory attention focused exercise vs aerobic training in Parkinson's disease. Mov Disord. 2009 Jun 15;24(8):1132-8. doi: 10.1002/mds.22469.

Reference Type BACKGROUND
PMID: 19373930 (View on PubMed)

Sage MD, Almeida QJ. A positive influence of vision on motor symptoms during sensory attention focused exercise for Parkinson's disease. Mov Disord. 2010 Jan 15;25(1):64-9. doi: 10.1002/mds.22886.

Reference Type BACKGROUND
PMID: 19938164 (View on PubMed)

Nieuwboer A, Kwakkel G, Rochester L, Jones D, van Wegen E, Willems AM, Chavret F, Hetherington V, Baker K, Lim I. Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial. J Neurol Neurosurg Psychiatry. 2007 Feb;78(2):134-40. doi: 10.1136/jnnp.200X.097923.

Reference Type BACKGROUND
PMID: 17229744 (View on PubMed)

Comella CL, Stebbins GT, Brown-Toms N, Goetz CG. Physical therapy and Parkinson's disease: a controlled clinical trial. Neurology. 1994 Mar;44(3 Pt 1):376-8. doi: 10.1212/wnl.44.3_part_1.376.

Reference Type BACKGROUND
PMID: 8145901 (View on PubMed)

Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.

Reference Type DERIVED
PMID: 38588457 (View on PubMed)

Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.

Reference Type DERIVED
PMID: 36602886 (View on PubMed)

Related Links

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http://www.wlu.ca/homepage.php?grp_id=2234

The Sun Life Movement Disorders Research and Rehabilitation Centre, based out of Wilfrid Laurier University, facilitates relevant research on Parkinson's disease.

Other Identifiers

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225510

Identifier Type: -

Identifier Source: org_study_id