Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

NCT ID: NCT01245374

Last Updated: 2017-02-27

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2011-04-30

Brief Summary

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This study is conducted in Europe. The aim of this study is to compare the easiness of use of Norditropin NordiFlex® device to the device previously used by patients or parents.

Detailed Description

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Conditions

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Growth Hormone Disorder Growth Hormone Deficiency in Children Foetal Growth Problem Small for Gestational Age Genetic Disorder Turner Syndrome Chronic Kidney Disease Chronic Renal Insufficiency Delivery Systems

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Nordiflex Norditropin®

Individually adjusted dose administered with Norditropin NordiFlex® for 6 weeks. Dosage depended on age, weight, etiologies and according to the summary of product characteristics (SPC)

Group Type EXPERIMENTAL

Norditropin NordiFlex®

Intervention Type DEVICE

Daily administration by a subcutaneous injection (under the skin). Starting dose and frequency will be determined by the physician as part of normal clinical practice

Interventions

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Norditropin NordiFlex®

Daily administration by a subcutaneous injection (under the skin). Starting dose and frequency will be determined by the physician as part of normal clinical practice

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Children who can receive Norditropin® (somatropin) treatment according to the product labelling
* Treated with growth hormone for at least one year

Exclusion Criteria

* Contraindications to Norditropin® growth hormone therapy
* Known or suspected hypersensitivity to somatropin or related products
* The receipt of any investigational medicinal product within 3 months prior to study start
* Life threatening disease, for example cancer
* Pregnancy or the intention of becoming pregnant
Minimum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Global Clinical Registry (GCR, 1452)

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Novo Nordisk Investigational Site

Paris La Défense Cedex, , France

Site Status

Countries

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France

References

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Tauber M, Jaquet D, Jesuran-Perelroizen M, Petrus M, Bertrand AM, Coutant R; NordiFlex(R) French Study Group. User assessment of Norditropin NordiFlex((R)), a new prefilled growth hormone pen: a Phase IV multicenter prospective study. Patient Prefer Adherence. 2013 May 24;7:455-62. doi: 10.2147/PPA.S43460. Print 2013.

Reference Type RESULT
PMID: 23737664 (View on PubMed)

Related Links

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http://novonordisk-trials.com

Clinical Trials at Novo Nordisk

Other Identifiers

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U1111-1117-1194

Identifier Type: OTHER

Identifier Source: secondary_id

2009-017387-16

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

GH-3826

Identifier Type: -

Identifier Source: org_study_id

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