Intrapartum Hydration

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2015-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine that maternal hydration during labor with fluids containing glucose at a rate of 125 ml per hour does not affect the duration of labor compared to Ringer Lactate at a rate of 250 ml per hour.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of Increased IV Hydration on Nulliparous Women Undergoing an Induction of Labor

NCT02989571

Labor; Forced or Induced, Affecting Fetus or Newborn

COMPLETED EARLY_PHASE1

A Trial of Intravenous Fluids During Labor

NCT01110005

Ketosis

COMPLETED NA

Study of the Fluid Intake Effect During Labour

NCT06371742

Labor Complication

COMPLETED

Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas

NCT01904617

Length of Labor Second Stage of Labor Intravenous Hydration of Labor

COMPLETED NA

Gastric Emptying of Water and Sports Drink in Labor

NCT04229043

Pregnancy Gastric Emptying

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

During labor it is a common practice that the parturient is fastening and having fluid replacement through intravenous hydration (IVH), the rational being to avoid aspiration of gastric content in a situation of need for urgent intervention and general anesthesia with tracheal intubation. It is acceptable to infuse 125 ml per hour of a physiological solution that does not contain sugar, but the volume is not adjusted to the weight of mother, the level of effort or relaxation she is experiencing and it may well be below the required amount. From studies in the field of sport medicine it is clear that the amount of fluid reaching the muscle has an impact on the efficiency of the muscle at the level of tissue and the level of personal achievement in sports. Only few studies dealt with the amount and contents of IVH during labor that will be sufficient and meet all physiologic requirements of the parturient and her fetus.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Labor Stage, First Labor Stage, Second

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

0.9% Saline with glucose 5%

rate of infusion is 125cc/h

Group Type ACTIVE_COMPARATOR

0.9% Saline with glucose 5%

Intervention Type OTHER

intravenous hydration at a rate of 125 ml per hour during labor

Ringer lactate

rate of infusion is 250cc/h

Group Type ACTIVE_COMPARATOR

Ringer lactate

Intervention Type OTHER

intravenous hydration at a rate of 250 ml per hour during labor

Ringer lactate - Controls

rate of infusion is 125cc/h

Group Type ACTIVE_COMPARATOR

Ringer lactate - Controls

Intervention Type OTHER

intravenous hydration at a rate of 125 ml per hour during labor

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

0.9% Saline with glucose 5%

intravenous hydration at a rate of 125 ml per hour during labor

Intervention Type OTHER

Ringer lactate

intravenous hydration at a rate of 250 ml per hour during labor

Intervention Type OTHER

Ringer lactate - Controls

intravenous hydration at a rate of 125 ml per hour during labor

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Nulliparous women
* Gestational age 37-41 weeks
* Cervical dilatation 1-3 cm
* Vertex presentation
* Singleton

Exclusion Criteria

* Diabetes
* Preeclampsia
* Intra uterine fetal growth restriction
* Duration of labor less than an hour
* Maternal chronic disease
* Maternal fever upon admission.

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No