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The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation

NCT ID: NCT01241175

Last Updated: 2010-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Study Classification

INTERVENTIONAL

Brief Summary

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The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non ocular surgery

Detailed Description

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Conditions

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Increased Intra Ocular Pressure (IOP)

Keywords

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IOP ophthalmic anesthesia magnesium sulfate

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Caregivers Outcome Assessors

Study Groups

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magnesium sulfate

Group Type EXPERIMENTAL

Magnesium Sulfate

Intervention Type DRUG

normal saline

Group Type PLACEBO_COMPARATOR

normal saline

Intervention Type DRUG

Interventions

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Magnesium Sulfate

Intervention Type DRUG

normal saline

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 18 to 38 years old
* ASA I
* scheduled for elective ENT ambulatory surgeries under general anesthesia

Exclusion Criteria

* specific major hepatic, renal and cardio-vascular disease
* known to have allergic reaction to magnesium sulphate or other drugs , -hypermagnesemia
* hypocalcemia
* anuria
* heart block
* pregnancy
* any degree of renal insufficiency
* digitalised patients
* positive history of glaucoma or intra ocular hypertension
* refused to participate
Minimum Eligible Age

18 Years

Maximum Eligible Age

38 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shiraz University of Medical Sciences

OTHER

Sponsor Role lead

Principal Investigators

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Hilda Mahmoudi, M.D

Role: STUDY_DIRECTOR

Shiraz University of Medical Sciences

Locations

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Shiraz University of Medical Sciences

Shiraz, Fars, Iran

Site Status

Countries

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Iran

Other Identifiers

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4286

Identifier Type: -

Identifier Source: org_study_id