Persistent Pulmonary Artery Hypertension After Valve Replacement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-31

Study Completion Date

2012-03-31

Brief Summary

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Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome.

Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH.

Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.

Detailed Description

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Conditions

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Persistent Severe PH After Valve Therapy

Keywords

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Valve replacement pulmonary hypertension long term follow up

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Valve replacement

Patients undergoing valve replacement for severe valve disease will be screened for study entry

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Proven pulmonary hypertension before valve replacement and informed consent for data acquisition

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Universitiy of Bonn, Medizinische Klinik und Poliklinik II

Locations

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Medizinische Klinik II, University of Bonn

Bonn, , Germany

Site Status

Countries

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Germany

Central Contacts

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Christoph Hammerstingl, MD

Role: CONTACT

Phone: +4922815951

Email: [email protected]

Dirk Skowasch, MD, PhD

Role: CONTACT

Phone: +4922816076

Email: [email protected]

Facility Contacts

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Robert Schueler, MD

Role: primary

Other Identifiers

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UKB_001_2010

Identifier Type: -

Identifier Source: org_study_id