Multicentre Prospective Cohort Study of Patients With Chronic Alcoholic and/or Metabolic Liver Disease
NCT ID: NCT01237574
Last Updated: 2021-03-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
527 participants
OBSERVATIONAL
2010-11-23
2020-12-12
Brief Summary
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The aim of this prospective cohort is to describe the natural history of patients with chronic liver disease due to alcohol or metabolic disease and to identify factors associated with complications of these liver diseases (cirrhosis, hepatocellular carcinoma, ascites. ..).
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Patients
Patients with chronic alcoholic and/or metabolic liver disease
Intervention according to the standard of care.
Every 6 months, patients will have clinical, biological and morphological evaluation according to the standard of care.
Interventions
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Intervention according to the standard of care.
Every 6 months, patients will have clinical, biological and morphological evaluation according to the standard of care.
Eligibility Criteria
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Inclusion Criteria
* chronic liver disease (liver biopsy with bridging fibrosis or cirrhosis) or non-invasive markers of fibrosis (fibrotest \> 0.58, FibroScan \> 7.9 kPa)
* no decompensated cirrhosis
* chronic alcohol use and/or metabolic syndrome (at least 3 criteria of metabolic syndrome)
* Written informed consent
* Patient covered by the French health insurance system
Exclusion Criteria
* Other cirrhosis causes
* Impossibility of regular follow-up
* Under guardianship major Patient
* Presence of focal hurt suggestive of CHC
* pregnant women
* cirrhosis complication
* Child-pugh score superior or equal to 7
18 Years
ALL
No
Sponsors
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University Hospital, Bordeaux
OTHER
Responsible Party
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Locations
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CHU d'Angers
Angers, , France
CHU de Besançon - Hôpital Jean Minjoz
Besançon, , France
CH Pierre Oudot
Bourgoin, , France
CHU de Brest - Hôpital La Cavale Blanche
Brest, , France
CHU de Caen
Caen, , France
CH de Chateauroux
Châteauroux, , France
CHU Clermont-Ferrand - Hôpital Estaing
Clermont-Ferrand, , France
CH Laennec
Creil, , France
CHU de Grenoble - Hôpital Albert Michallon
Grenoble, , France
CH Le Mans
Le Mans, , France
GH-ICL - Hôpital Saint Philibert
Lille, , France
CH de Limoges - Hôpital Dupuytren
Limoges, , France
HCL - Hôpital Hôtel Dieu
Lyon, , France
APHM - Hôpital La Conception
Marseille, , France
Hôpital Saint-Joseph
Marseille, , France
CH de Montauban
Montauban, , France
CHU de Nancy - Hôpital de Brabois
Nancy, , France
CHU de Nice - Hôpital Archet 2
Nice, , France
Hôpital Carémeau
Nîmes, , France
CHR Orléans - Hôpital La Source
Orléans, , France
APHP - Hôpital Bicêtre
Paris, , France
APHP - Hôpital Jean Verdier
Paris, , France
APHP - Hôpital Paul Brousse
Paris, , France
APHP - Hôpital Pitié Salpetrière
Paris, , France
APHP - Hôpital Saint-Antoine
Paris, , France
APHP - Hôpital Tenon
Paris, , France
APHP Hôpital Cochin
Paris, , France
APHP- CHU Henri Mondor
Paris, , France
CH de Perpignan - Hôpital Saint-Jean
Perpignan, , France
CHU de Bordeaux - Hôpital du Haut-Lévêque
Pessac, , France
CHRU de Poitiers
Poitiers, , France
CHU de Reims - Hôpital Robert Debré
Reims, , France
CHU de Rouen
Rouen, , France
CHRU de Strasbourg - Nouvel Hôpital Civil
Strasbourg, , France
CHU de Toulouse - Hôpital Purpan
Toulouse, , France
CHRU de Tours - Hôpital Trousseau
Tours, , France
Countries
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Other Identifiers
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CHUBX 2010/38
Identifier Type: -
Identifier Source: org_study_id
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