Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
NCT ID: NCT01236950
Last Updated: 2010-11-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2007-04-30
2008-09-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Delmopinol mouthrinse
Subjects use the delmopinol mouthrinse
Delmopinol mouthrinse
Commercial mouthrinse with manufacturer's use indication
Control
Subjects with no use of mouthrinse
No interventions assigned to this group
Essential oils mouthrinse
Subjects using the essential oils mouthrinse
Essential oils mouthrinse
Commercial mouthrinse with manufacturer's use indication
Interventions
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Essential oils mouthrinse
Commercial mouthrinse with manufacturer's use indication
Delmopinol mouthrinse
Commercial mouthrinse with manufacturer's use indication
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Signature of consent form
* Have, at least, two quadrant with 6 teeth each
* Gingival Index at baseline less than 3
* Presence of dental plaque
Exclusion Criteria
* Dental Hygiene appointment in the past 6 months
* Use of antibiotics in teh past 3 months
* Presence of extensive caries and fractures of teeth
15 Years
ALL
Yes
Sponsors
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Instituto Piaget
OTHER
University of Lisbon
OTHER
Responsible Party
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Faculdade de Medicina Dentária da Universidade de Lisboa
Principal Investigators
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Mario F Bernardo, PhD
Role: STUDY_DIRECTOR
Faculdade de Medicina Dentária da Universidade de Lisboa
Locations
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Faculdade de Medicina Dentária da Universidade de Lisboa
Lisbon, Lisbon District, Portugal
Countries
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References
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Abbott DM, Gunsolley JC, Koertge TE, Payne EL. The relative efficacy of 0.1% and 0.2% delmopinol mouthrinses in inhibiting the development of supragingival dental plaque and gingivitis in man. J Periodontol. 1994 May;65(5):437-41. doi: 10.1902/jop.1994.65.5.437.
Addy M, Moran J, Newcombe RG. Meta-analyses of studies of 0.2% delmopinol mouth rinse as an adjunct to gingival health and plaque control measures. J Clin Periodontol. 2007 Jan;34(1):58-65. doi: 10.1111/j.1600-051X.2006.01013.x. Epub 2006 Nov 20.
Baehni PC, Takeuchi Y. Anti-plaque agents in the prevention of biofilm-associated oral diseases. Oral Dis. 2003;9 Suppl 1:23-9. doi: 10.1034/j.1601-0825.9.s1.5.x.
Barnett ML. The rationale for the daily use of an antimicrobial mouthrinse. J Am Dent Assoc. 2006 Nov;137 Suppl:16S-21S. doi: 10.14219/jada.archive.2006.0408.
Fine DH, Furgang D, Barnett ML, Drew C, Steinberg L, Charles CH, Vincent JW. Effect of an essential oil-containing antiseptic mouthrinse on plaque and salivary Streptococcus mutans levels. J Clin Periodontol. 2000 Mar;27(3):157-61. doi: 10.1034/j.1600-051x.2000.027003157.x.
Gordon JM, Lamster IB, Seiger MC. Efficacy of Listerine antiseptic in inhibiting the development of plaque and gingivitis. J Clin Periodontol. 1985 Sep;12(8):697-704. doi: 10.1111/j.1600-051x.1985.tb00941.x.
Ouhayoun JP. Penetrating the plaque biofilm: impact of essential oil mouthwash. J Clin Periodontol. 2003;30 Suppl 5:10-2. doi: 10.1034/j.1600-051x.30.s5.4.x.
Other Identifiers
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9/2006a
Identifier Type: -
Identifier Source: org_study_id