Biomarkers of Bone Resorption in Metastatic Prostate Cancer

NCT ID: NCT01233557

Last Updated: 2015-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-09-30

Study Completion Date

2014-08-31

Brief Summary

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Biomarkers of bone resorption will be measured in the blood of patients with bone metastases from prostate cancer during the course of their illness. Changes in these biomarkers will be correlated with the patient's treatment with antiandrogen therapy and bisphosphonates and the response and/or progression of their cancer. It is hoped that serial measurement of these biomarkers may allow therapeutic monitoring in the future with successful individualisation of bisphosphonate therapy for metastatic prostate cancer.

Detailed Description

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Conditions

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Metastatic Prostate Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Bone Metastases

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* prostate cancer with bone metastases
* hormone sensitive

Exclusion Criteria

* inadequate renal function
* ongoing dental problems
* previous bisphosphonate therapy
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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University of Aberdeen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Donald Bissett, M.D.

Role: PRINCIPAL_INVESTIGATOR

NHS Grampian

Locations

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Aberdeen Royal Infirmary

Aberdeen, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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10/S0802/36

Identifier Type: -

Identifier Source: org_study_id

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