The Akloma Tinnitus Patch in Patients With Manifested Tinnitus

NCT ID: NCT01226108

Last Updated: 2011-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Brief Summary

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OBJECTIVES:

Primary Objective The primary objective will be a decrease of inconvenience with at least 10% for at least 50% of the subjects.

Secondary Objectives

The secondary objective will be to:

To evaluate if the patch can improve the tinnitus patient's quality of life and sleep quality.

METHODOLOGY

Study Design:

An open safety and performance clinical investigation of the antinitus patch in patients with manifested tinnitus.

Treatment Duration:

1 patch per day for 3 weeks

Primary Endpoint:

Tinnitus severity questionnaire (TSQ)

Performance Parameters:

Tinnitus severity questionnaire (TSQ) and numerical rating scale (NRS) measuring tinnitus annoyance.

Quality of life and sleep quality

Safety Parameters: Adverse Reactions

Detailed Description

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Conditions

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Tinnitus

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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antinitus patch

One patch per day, Duration: three weeks, Administration: behind the ear

Group Type ACTIVE_COMPARATOR

Patch

Intervention Type DEVICE

One patch per day, Duration: three weeks, Administration: behind the ear

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Interventions

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Patch

One patch per day, Duration: three weeks, Administration: behind the ear

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Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adults of both sexes \> 18 years of age
* Signed informed consent
* Patients who have suffered from tinnitus for ≥ 4 weeks before study entry
* Manifested tinnitus grade II or above on the Klockhoff-Lindblom tinnitus severity grading scale.
* Tinnitus score of 5 or above (numerical rating scale for tinnitus annoyance)
* Pure tone averages better than 40 dB in the worse hearing ear.

Exclusion Criteria

* Pregnant or lactating women
* Malignancy or other serious medical conditions
* Skin disease
* Simultaneous or previous (within 30 days prior to study entry) participation in a clinical study using experimental drugs or devices.
* Severe psychiatric disorder
* Serious suicidal risk
* Patients who have started treatment or made changes in treatment with drugs known to influence tinnitus within 6 weeks before study start.
* Patients with untreated high blood pressure ≥140/90 mmHg
* Other tinnitus treatment within 6 weeks before study entry.
* Previous use of the Antinitus patch
* Known allergy or sensitivity to any of the compounds in the Antinitus or the placebo patches.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Akloma Bioscience AB

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Peter Åhnblad

Role: PRINCIPAL_INVESTIGATOR

Sickla ÖNH-center / Supramed AB

Locations

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Sickla ÖNH-center, Atlashuset Planiavägen 5

Nacka, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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Aktin study

Identifier Type: -

Identifier Source: org_study_id