Trial Outcomes & Findings for TOCCATA - Touch+™ for Catheter Ablation (NCT NCT01223469)

NCT ID: NCT01223469

Last Updated: 2019-01-30

Results Overview

For Right SVT patients 7 days (±1 day) following the index procedure or until hospital discharge whichever is longer. For AF patients 3 months (±2 weeks)following the index procedure.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

77 participants

Primary outcome timeframe

3 months for AF arm; 7 days for the right SVT arm

Results posted on

2019-01-30

Participant Flow

Participant milestones

Participant milestones
Measure
Atrial Fibrillation
Contact force assisted irrigated RF ablation: radiofrequency ablation of atrial fibrillation.
Right-sided Supraventricular Tachycardia
Contact force assisted irrigated RF ablation: radiofrequency ablation of SVT
Overall Study
STARTED
34
43
Overall Study
COMPLETED
34
43
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

TOCCATA - Touch+™ for Catheter Ablation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Atrial Fibrillation
n=34 Participants
Contact force assisted irrigated RF ablation: radiofrequency ablation of atrial fibrillation.
Right-sided Supraventricular Tachycardia
n=43 Participants
Contact force assisted irrigated RF ablation: radiofrequency ablation of SVT
Total
n=77 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
9 Participants
n=5 Participants
11 Participants
n=7 Participants
20 Participants
n=5 Participants
Age, Categorical
>=65 years
25 Participants
n=5 Participants
32 Participants
n=7 Participants
57 Participants
n=5 Participants
Sex: Female, Male
Female
11 Participants
n=5 Participants
14 Participants
n=7 Participants
25 Participants
n=5 Participants
Sex: Female, Male
Male
23 Participants
n=5 Participants
29 Participants
n=7 Participants
52 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 3 months for AF arm; 7 days for the right SVT arm

For Right SVT patients 7 days (±1 day) following the index procedure or until hospital discharge whichever is longer. For AF patients 3 months (±2 weeks)following the index procedure.

Outcome measures

Outcome measures
Measure
Atrial Fibrillation
n=34 Participants
Contact force assisted irrigated RF ablation: radiofrequency ablation of atrial fibrillation.
Right-sided Supraventricular Tachycardia
n=43 Participants
Contact force assisted irrigated RF ablation: radiofrequency ablation of SVT.
Number of Subjects With Operative and Post-operative Serious Adverse Events
4 participants
1 participants

Adverse Events

Atrial Fibrillation

Serious events: 4 serious events
Other events: 0 other events
Deaths: 0 deaths

Right-sided Supraventricular Tachycardia

Serious events: 1 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Serious adverse events
Measure
Atrial Fibrillation
n=34 participants at risk
Contact force assisted irrigated RF ablation: radiofrequency ablation of atrial fibrillation.
Right-sided Supraventricular Tachycardia
n=43 participants at risk
Contact force assisted irrigated RF ablation: radiofrequency ablation of SVT.
Cardiac disorders
Sinus Bradycardia
2.9%
1/34 • Number of events 1
2.3%
1/43 • Number of events 1
Cardiac disorders
Tamponade
2.9%
1/34 • Number of events 1
0.00%
0/43
Vascular disorders
Groin Bleeding
2.9%
1/34 • Number of events 1
0.00%
0/43
Cardiac disorders
Stroke
2.9%
1/34 • Number of events 1
0.00%
0/43

Other adverse events

Adverse event data not reported

Additional Information

Hendrik Lambert PhD, VP of Clinical and Regulatory Affairs

St. Jude Medical/Endosense

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place