Input of C11-Choline PET/CT in Localization of Parathyroid Adenoma
NCT ID: NCT01221896
Last Updated: 2010-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2011-01-31
Brief Summary
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Preoperative localization of a PTA has been previously documented in multiple series, and is usually based on scintigraphy and on US.
Currently, the conventional technique for localization of a PTA is a dual-isotope scan with Tc99m-MIBI and Tc99m pertechnetate. This study is acquired over at least 3 hours, includes two i.v. injections and the patient has to stay 15-30 min per acquisition under the camera.
In addition, there is no anatomical imaging and further correlation with US is usually recommended.
In contrast, PET/CT study with C11-Choline takes as long as 10 min., includes one injection, and provides data of higher resolution of functional (PET) and anatomical imaging (CT).
Furthermore, dosimetric data shows that the total effective dose from Tc99mMIBI and Tc99m pertechnetate injection is (without CT): 0.5957 rem; and from C11-Choline injection and CT of a chest is: 0.3128 - 0.8628rem.
Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Hyperparathyroidism
Patients with hyperparathyroidism, prior to surgery.
C11-Choline PET/CT
Interventions
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C11-Choline PET/CT
Eligibility Criteria
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Inclusion Criteria
18 Years
80 Years
ALL
No
Sponsors
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Hadassah Medical Organization
OTHER
Locations
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Hadassah Hebrew University Medical Center
Jerusalem, , Israel
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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choline2010-HMO-CTIL
Identifier Type: -
Identifier Source: org_study_id