Effects of Physical Activity During Pregnancy on the Newborn's Cognitive Function

NCT ID: NCT01220778

Last Updated: 2010-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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Background: It is now generally accepted that an active lifestyle is beneficial for cognition, but can these benefits be transmitted for the active pregnant woman to her unborn child? This has been demonstrated in rats where the pups born of mothers who exercised during pregnancy had increased hippocampal neurogenesis and better memory and learning capabilities. Human studies tend to confirm this by looking at behavioral results, ie. better orientation and state regulation skills in newborns. The aim of the present study is to verify this on the electrophysiological level and to determine the effects of an active lifestyle during pregnancy on the newborn's brain development.

Methods: 60 pregnant women will be included in a randomized controlled trial. The exercise group will be asked to exercise a minimum of 20 minutes, 3 times per week, at a minimal intensity of 55% of their maximal aerobic capacity. The control group will not be given exercise counselling. Newborns' brain activity will be recorded using electroencephalography (EEG) 10 days post partum. The primary outcome measure will be the amplitude and latency of the mismatch negativity (MMN), a component of the auditory event-related potential (ERP) that can be used to investigate the auditory sensory memory.

Detailed Description

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Conditions

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Pregnancy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Study Groups

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Exercise

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

Control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* First trimester of pregnancy
* 20 to 35 years of age
* Pre-pregnancy BMI between 18 and 25
* Primipara
* Without any known health issues
* Use of folic acid

Exclusion Criteria

* Use of alcohol, cigarettes or illegal drugs
* Pregnancy complications
* Unable or unwilling to breastfeed
* Excessive or insufficient weight gain
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Université de Montréal

OTHER

Sponsor Role lead

Principal Investigators

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Elise L.LeMoyne

Role: PRINCIPAL_INVESTIGATOR

Université de Montréal

Locations

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Cepsum

Montreal, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Elise L. LeMoyne

Role: CONTACT

514-343-6111 ext. 5380

Facility Contacts

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Elise L.LeMoyne

Role: primary

514-343-6111 ext. 5380

References

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LeMoyne EL, Curnier D, St-Jacques S, Ellemberg D. The effects of exercise during pregnancy on the newborn's brain: study protocol for a randomized controlled trial. Trials. 2012 May 29;13:68. doi: 10.1186/1745-6215-13-68.

Reference Type DERIVED
PMID: 22643160 (View on PubMed)

Other Identifiers

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CERSS-2010-951-P

Identifier Type: -

Identifier Source: org_study_id