Radiocontrast Media Induced Hyponatremia

NCT ID: NCT01219270

Last Updated: 2010-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-10-31

Study Completion Date

2011-06-30

Brief Summary

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Osmolality of contrast media can be resulted in translocational hyponatremia after percutaneous coronary intervention.

Detailed Description

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Radiocontrast media after percutaneous coronary interventioncan lead to increased osmolaliry of plasma, which results in translocational hyponatremia.

The investigator will exam the incidence of hyponatremia after percutaneous coronary intervention, and will evaluate the underlying mechanism related to hyponatremia including translocational hyponatremia, or osmotic natriuresis.

Conditions

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Percutaneous Coronary Intervention

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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GFR >= 60

MDRD eGFR 60 or more

No interventions assigned to this group

GFR <60

Under MDRD eGFR 60

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who receive contrast media during percutaneous coronary intervention

Exclusion Criteria

* Patients who have sensitivity to contrast media.
* Liver cirrhosis
* Hypothyroidism
* SIADH
* Patients who receive IVIG or mannitol.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gachon University Gil Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Gachon University Gil Medical Center

Principal Investigators

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Sejoong Kim, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Gachon University Gil Medical Center

Locations

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Gachon University Gil Hospital

Incheon, , South Korea

Site Status RECRUITING

Countries

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South Korea

Facility Contacts

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Wookyung Chung, MD, PhD

Role: primary

+82-32-460-3431

References

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Aronson D, Dragu RE, Nakhoul F, Hir J, Miller A, Boulos M, Zinder O, Green J, Mittleman MA, Markiewicz W. Hyponatremia as a complication of cardiac catheterization: a prospective study. Am J Kidney Dis. 2002 Nov;40(5):940-6. doi: 10.1053/ajkd.2002.36324.

Reference Type BACKGROUND
PMID: 12407638 (View on PubMed)

Other Identifiers

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Hyponatremia-GUGH

Identifier Type: -

Identifier Source: org_study_id