Measuring and Reducing Excessive Infant Crying

NCT ID: NCT01217658

Last Updated: 2015-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2015-09-30

Brief Summary

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Excessive infant crying (EIC) is likely to increase the risk of child abuse. The investigators propose a randomized trial using an intervention based on recommendations of Karp. The investigators will systematically identify 170 term infants with EIC and conduct assessments in the home at 6-8 weeks age to test the hypothesis that the intervention reduces mean infant hours of night-time crying, increases maternal soothing behaviors and improves parental anxiety and depression.

Detailed Description

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Hypotheses: The soothing techniques taught to study parents 2-3 wks after birth augment parental soothing skills and reduces infant crying at night (primary outcome) and parental sleep loss, distress, \& depression assessed in the home by a masked nurse at 8 wks.

Methods: Term singleton infants with EIC (\> 3 hrs/24h) recruited through a program offered to parents at our hospital (4,700 births/yr) will be seen in our clinic 2-3 wks after birth. Consenting families (n=178) will be randomized to standard colic counseling (American Academy of Pediatrics) or to the intervention (adding nurse instruction plus a video and pamphlets). At 8 wks a study nurse will assess parental sleep and distress (Brief Symptom Inventory-18), place dosimeters in rooms where the infant sleeps and spends most time, and apply the actigraph at the ankle. She will collect the devices 5 days later, perform a physical exam at a usual feeding time (when EIC is likely), record infant \& maternal behaviors during crying/feeding for the next 15 minutes using unobtrusive, validated methods (Tyson, 1992), and provide maternal support if desired. Standard statistical tests will be used (alpha=0.05; beta = 0.20; effect size =0.5 SD, power = .90).

Conditions

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Infant Colic Postpartum Depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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The Happiest Baby on The Block

Those receiving the intervention will be trained in the infant soothing techniques outlined in "The Happiest Baby on the Block".

Group Type EXPERIMENTAL

The Happiest Baby on The Block

Intervention Type BEHAVIORAL

Those receiving the intervention will be trained in the infant soothing techniques outlined in "The Happiest Baby on the Block".

AAP Education

Those receiving the control group allocation will be counseled in the American Academy of Pediatrics guidelines regarding Infant Colic (AAP Infant Colic counseling).

Group Type ACTIVE_COMPARATOR

AAP Infant Colic counseling

Intervention Type BEHAVIORAL

Those receiving the control group allocation will be counseled using the American Academy of Pediatrics material for Infant Colic.

Interventions

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The Happiest Baby on The Block

Those receiving the intervention will be trained in the infant soothing techniques outlined in "The Happiest Baby on the Block".

Intervention Type BEHAVIORAL

AAP Infant Colic counseling

Those receiving the control group allocation will be counseled using the American Academy of Pediatrics material for Infant Colic.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* term, singleton neonates
* otherwise healthy
* parent must have at least a 6th grade understanding of English or Spanish
* infant must have colic (greater than 3 hours of crying per day)
* OR the infant's crying causes excessive stress on the either parent

Exclusion Criteria

* cannot have a condition which would reasonably impact alertness or behavior
Minimum Eligible Age

3 Weeks

Maximum Eligible Age

5 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

Sponsor Role collaborator

The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Christopher Greeley

Associate Professor - Pediatrics

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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K23HD065872

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HSC-MS-10-0392

Identifier Type: -

Identifier Source: org_study_id